GO Annotations Graph

• Symbol: Inppl1
• Name: inositol polyphosphate phosphatase-like 1
• ID: MGI:1333787

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	ISO	J:155856
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	IBA	J:265628
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:201313
Molecular Function	GO:0005515	protein binding	IPI	J:85624
Molecular Function	GO:0042169	SH2 domain binding	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:85624
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9680646
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682158
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682182
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:85624
Biological Process	GO:0007015	actin filament organization	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0044255	cellular lipid metabolic process	IMP	J:96048
Biological Process	GO:0001958	endochondral ossification	ISO	J:164563
Biological Process	GO:0006897	endocytosis	ISO	J:164563
Biological Process	GO:0006006	glucose metabolic process	IMP	J:96443
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0032957	inositol trisphosphate metabolic process	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:85624
Biological Process	GO:0008156	negative regulation of DNA replication	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:96048
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	IBA	J:265628
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:155856
Biological Process	GO:0010977	negative regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	IMP	J:172725
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	IEA	J:72247
Biological Process	GO:0009791	post-embryonic development	IMP	J:96443
Biological Process	GO:0050776	regulation of immune response	IBA	J:265628
Biological Process	GO:0032868	response to insulin	IMP	J:96443
Biological Process	GO:0097178	ruffle assembly	IMP	J:172725