GO Annotations Graph

• Symbol: Ccr6
• Name: C-C motif chemokine receptor 6
• ID: MGI:1333797

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019957	C-C chemokine binding	ISO	J:164563
Molecular Function	GO:0019957	C-C chemokine binding	IDA	J:233575
Molecular Function	GO:0016493	C-C chemokine receptor activity	IDA	J:233575
Molecular Function	GO:0016493	C-C chemokine receptor activity	ISO	J:164563
Molecular Function	GO:0004950	chemokine receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:233575
Molecular Function	GO:0005515	protein binding	IPI	J:51311
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:200103
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:190936
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0036126	sperm flagellum	IDA	J:233566
Cellular Component	GO:0036126	sperm flagellum	ISO	J:164563
Cellular Component	GO:0097225	sperm midpiece	ISO	J:164563
Cellular Component	GO:0097524	sperm plasma membrane	ISO	J:164563
Cellular Component	GO:0097524	sperm plasma membrane	IDA	J:233566
Cellular Component	GO:0097228	sperm principal piece	ISO	J:164563
Cellular Component	GO:0097228	sperm principal piece	IDA	J:233566
Biological Process	GO:0019722	calcium-mediated signaling	ISO	J:164563
Biological Process	GO:0060326	cell chemotaxis	ISO	J:164563
Biological Process	GO:0006935	chemotaxis	ISO	J:164563
Biological Process	GO:0006935	chemotaxis	IDA	J:233575
Biological Process	GO:1904155	DN2 thymocyte differentiation	IMP	J:233563
Biological Process	GO:1904156	DN3 thymocyte differentiation	IMP	J:233563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0006955	immune response	IBA	J:265628
Biological Process	GO:0048290	isotype switching to IgA isotypes	IMP	J:233674
Biological Process	GO:0002523	leukocyte migration involved in inflammatory response	IMP	J:142071
Biological Process	GO:0072676	lymphocyte migration	IMP	J:233674
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:2000510	positive regulation of dendritic cell chemotaxis	ISO	J:155856
Biological Process	GO:2000510	positive regulation of dendritic cell chemotaxis	IBA	J:265628
Biological Process	GO:0010634	positive regulation of epithelial cell migration	ISO	J:155856
Biological Process	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation	ISO	J:164563
Biological Process	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation	IDA	J:233566
Biological Process	GO:2000404	regulation of T cell migration	IMP	J:142071
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0072678	T cell migration	IDA	J:233563
Biological Process	GO:0072679	thymocyte migration	IDA	J:233563
Biological Process	GO:0072679	thymocyte migration	IBA	J:265628