Slc22a3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Slc22a3
solute carrier family 22 (organic cation transporter), member 3
MGI:1333817

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005330	dopamine:sodium symporter activity	ISO	J:155856
Molecular Function	GO:0008504	monoamine transmembrane transporter activity	IMP	J:138641
Molecular Function	GO:0008504	monoamine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005326	neurotransmitter transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005326	neurotransmitter transmembrane transporter activity	IMP	J:138641
Molecular Function	GO:0005326	neurotransmitter transmembrane transporter activity	IMP	J:138641
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	ISO	J:100021
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	ISO	J:73065
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	IDA	J:64862
Molecular Function	GO:0015651	quaternary ammonium group transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015651	quaternary ammonium group transmembrane transporter activity	ISO	J:73065
Molecular Function	GO:0015651	quaternary ammonium group transmembrane transporter activity	IDA	J:64862
Molecular Function	GO:0015606	spermidine transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0019534	toxin transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0019534	toxin transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0022857	transmembrane transporter activity	IDA	J:243491
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:333137
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0012505	endomembrane system	IDA	J:333164
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031966	mitochondrial membrane	IDA	J:333164
Cellular Component	GO:0043025	neuronal cell body	IDA	J:138641
Cellular Component	GO:0005886	plasma membrane	IDA	J:333137
Cellular Component	GO:0005886	plasma membrane	IDA	J:289076
Cellular Component	GO:0005886	plasma membrane	IDA	J:333164
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	J:52875
Biological Process	GO:0015872	dopamine transport	ISO	J:164563
Biological Process	GO:0015872	dopamine transport	IMP	J:138641
Biological Process	GO:0015872	dopamine transport	IMP	J:138641
Biological Process	GO:0015872	dopamine transport	ISO	J:155856
Biological Process	GO:0090494	dopamine uptake	ISO	J:164563
Biological Process	GO:0048241	epinephrine transport	ISO	J:164563
Biological Process	GO:0051625	epinephrine uptake	ISO	J:164563
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:100519
Biological Process	GO:0051608	histamine transport	ISO	J:164563
Biological Process	GO:0051608	histamine transport	IMP	J:138641
Biological Process	GO:0051608	histamine transport	IMP	J:100519
Biological Process	GO:0051615	histamine uptake	ISO	J:164563
Biological Process	GO:0051615	histamine uptake	IMP	J:100519
Biological Process	GO:0015844	monoamine transport	ISO	J:164563
Biological Process	GO:0015844	monoamine transport	IMP	J:69978
Biological Process	GO:0015844	monoamine transport	IMP	J:69978
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0015718	monocarboxylic acid transport	IMP	J:138641
Biological Process	GO:0006836	neurotransmitter transport	ISO	J:164563
Biological Process	GO:0006836	neurotransmitter transport	IMP	J:138641
Biological Process	GO:0015874	norepinephrine transport	ISO	J:164563
Biological Process	GO:0015874	norepinephrine transport	IMP	J:138641
Biological Process	GO:0051620	norepinephrine uptake	ISO	J:164563
Biological Process	GO:0015711	organic anion transport	ISO	J:155856
Biological Process	GO:0015695	organic cation transport	ISO	J:155856
Biological Process	GO:0015695	organic cation transport	ISO	J:73065
Biological Process	GO:0015695	organic cation transport	IDA	J:64862
Biological Process	GO:0015695	organic cation transport	ISO	J:100021
Biological Process	GO:0015850	organic hydroxy compound transport	IMP	J:138641
Biological Process	GO:0015697	quaternary ammonium group transport	ISO	J:155856
Biological Process	GO:0015697	quaternary ammonium group transport	IDA	J:64862
Biological Process	GO:0015697	quaternary ammonium group transport	ISO	J:73065
Biological Process	GO:0032098	regulation of appetite	IMP	J:90076
Biological Process	GO:0006837	serotonin transport	ISO	J:164563
Biological Process	GO:0006837	serotonin transport	IMP	J:138641
Biological Process	GO:0006837	serotonin transport	IMP	J:138641
Biological Process	GO:0051610	serotonin uptake	ISO	J:164563
Biological Process	GO:0015848	spermidine transport	ISO	J:155856
Biological Process	GO:1901998	toxin transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0042908	xenobiotic transport	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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