GO Annotations Graph

• Symbol: Mbd4
• Name: methyl-CpG binding domain protein 4
• ID: MGI:1333850

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IDA	J:50520
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	ISO	J:73065
Cellular Component	GO:0000785	chromatin	IDA	J:50520
Cellular Component	GO:0005737	cytoplasm	IDA	J:130115
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:130115
Cellular Component	GO:0005634	nucleus	IDA	J:50520
Biological Process	GO:0006974	DNA damage response	IMP	J:86055
Biological Process	GO:0006306	DNA methylation	TAS	J:69467
Biological Process	GO:0006281	DNA repair	IEA	J:72247
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:86055
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	IMP	J:86981
Biological Process	GO:0009314	response to radiation	IMP	J:86055