GO Annotations Graph

• Symbol: Gab2
• Name: growth factor receptor bound protein 2-associated protein 2
• ID: MGI:1333854

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	IDA	J:129191
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	IDA	J:129191
Molecular Function	GO:0005515	protein binding	IPI	J:97515
Molecular Function	GO:0005515	protein binding	IPI	J:146296
Molecular Function	GO:0005515	protein binding	IPI	J:129191
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:155856
Molecular Function	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	ISO	J:164563
Molecular Function	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2730846
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2730869
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9007126
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9007137
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9606621
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9606623
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9606789
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9607226
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9645128
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9645133
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9645136
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9674973
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9680646
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682158
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682182
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0016477	cell migration	IDA	J:75835
Biological Process	GO:0007229	integrin-mediated signaling pathway	IDA	J:75835
Biological Process	GO:0035556	intracellular signal transduction	ISO	J:155856
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:97515
Biological Process	GO:0030316	osteoclast differentiation	ISO	J:164563
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	IMP	J:70424
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010634	positive regulation of epithelial cell migration	IMP	J:203318
Biological Process	GO:0043306	positive regulation of mast cell degranulation	IMP	J:70424
Biological Process	GO:0007165	signal transduction	IBA	J:265628