GO Annotations Graph

• Symbol: Hsd17b10
• Name: hydroxysteroid (17-beta) dehydrogenase 10
• ID: MGI:1333871

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	ISO	J:164563
Molecular Function	GO:0047015	3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0018454	acetoacetyl-CoA reductase activity	ISO	J:155856
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:155856
Molecular Function	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity	IEA	J:72245
Molecular Function	GO:0106281	chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity	ISO	J:164563
Molecular Function	GO:0008709	cholate 7-alpha-dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	ISO	J:155856
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0106282	isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity	ISO	J:164563
Molecular Function	GO:0051287	NAD binding	ISO	J:155856
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:155856
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0005496	steroid binding	ISO	J:155856
Molecular Function	GO:0047035	testosterone dehydrogenase (NAD+) activity	ISO	J:164563
Molecular Function	GO:0030283	testosterone dehydrogenase [NAD(P)] activity	ISO	J:164563
Molecular Function	GO:0000049	tRNA binding	ISO	J:164563
Molecular Function	GO:0106283	ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:99578
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0042645	mitochondrial nucleoid	ISO	J:164563
Cellular Component	GO:0042645	mitochondrial nucleoid	IDA	J:213151
Cellular Component	GO:0030678	mitochondrial ribonuclease P complex	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:213151
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0043527	tRNA methyltransferase complex	ISO	J:164563
Biological Process	GO:0008209	androgen metabolic process	ISO	J:164563
Biological Process	GO:0008209	androgen metabolic process	IBA	J:265628
Biological Process	GO:0006699	bile acid biosynthetic process	ISO	J:164563
Biological Process	GO:0062173	brexanolone metabolic process	ISO	J:164563
Biological Process	GO:0008207	C21-steroid hormone metabolic process	ISO	J:164563
Biological Process	GO:0008210	estrogen metabolic process	ISO	J:164563
Biological Process	GO:0008210	estrogen metabolic process	IBA	J:265628
Biological Process	GO:0006635	fatty acid beta-oxidation	ISO	J:164563
Biological Process	GO:0006631	fatty acid metabolic process	IBA	J:265628
Biological Process	GO:0006550	isoleucine catabolic process	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:1990180	mitochondrial tRNA 3'-end processing	ISO	J:164563
Biological Process	GO:0097745	mitochondrial tRNA 5'-end processing	ISO	J:164563
Biological Process	GO:0070901	mitochondrial tRNA methylation	ISO	J:164563
Biological Process	GO:0007005	mitochondrion organization	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0008202	steroid metabolic process	IEA	J:60000
Biological Process	GO:0008033	tRNA processing	IEA	J:60000