GO Annotations Graph

• Symbol: Neurl1a
• Name: neuralized E3 ubiquitin protein ligase 1A
• ID: MGI:1334263

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:117595
Molecular Function	GO:0005515	protein binding	IPI	J:227382
Molecular Function	GO:0005515	protein binding	IPI	J:178916
Molecular Function	GO:0005515	protein binding	IPI	J:178916
Molecular Function	GO:0005515	protein binding	IPI	J:90054
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0045183	translation factor activity, non-nucleic acid binding	IDA	J:178916
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:178916
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IDA	J:178916
Cellular Component	GO:0097440	apical dendrite	IDA	J:178916
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:65922
Cellular Component	GO:0005737	cytoplasm	IDA	J:71088
Cellular Component	GO:0005737	cytoplasm	ISO	J:72105
Cellular Component	GO:0043197	dendritic spine	IDA	J:178916
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043204	perikaryon	IDA	J:178916
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:65922
Cellular Component	GO:0014069	postsynaptic density	IDA	J:178916
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0071230	cellular response to amino acid stimulus	IDA	J:178916
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:72105
Biological Process	GO:0007595	lactation	IMP	J:72105
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	ISO	J:164563
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	IBA	J:265628
Biological Process	GO:0007399	nervous system development	IBA	J:265628
Biological Process	GO:0007219	Notch signaling pathway	IEA	J:60000
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0060999	positive regulation of dendritic spine development	IDA	J:178916
Biological Process	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	IMP	J:71088
Biological Process	GO:0051491	positive regulation of filopodium assembly	IDA	J:178916
Biological Process	GO:0048170	positive regulation of long-term neuronal synaptic plasticity	IDA	J:178916
Biological Process	GO:0090129	positive regulation of synapse maturation	IDA	J:178916
Biological Process	GO:0006513	protein monoubiquitination	IDA	J:178916
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0007288	sperm axoneme assembly	IMP	J:72105