Vamp8 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Vamp8
vesicle-associated membrane protein 8
MGI:1336882

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019869	chloride channel inhibitor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:182470
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005484	SNAP receptor activity	ISO	J:155856
Molecular Function	GO:0005484	SNAP receptor activity	IBA	J:265628
Molecular Function	GO:0019905	syntaxin binding	ISO	J:155856
Molecular Function	GO:0019905	syntaxin binding	IBA	J:265628
Cellular Component	GO:0035577	azurophil granule membrane	ISO	J:164563
Cellular Component	GO:0045178	basal part of cell	IDA	J:137704
Cellular Component	GO:1990794	basolateral part of cell	IDA	J:137704
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:137704
Cellular Component	GO:0009986	cell surface	IDA	J:209479
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:189036
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005769	early endosome	TAS	J:51999
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0031902	late endosome membrane	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:155856
Cellular Component	GO:0005764	lysosome	IDA	J:236240
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0030496	midbody	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0098594	mucin granule	ISO	J:164563
Cellular Component	GO:0098594	mucin granule	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:143718
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0055037	recycling endosome	ISO	J:155856
Cellular Component	GO:0030141	secretory granule	IDA	J:133652
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:164563
Cellular Component	GO:0031201	SNARE complex	ISO	J:164563
Cellular Component	GO:0031201	SNARE complex	ISO	J:155856
Cellular Component	GO:0031201	SNARE complex	IBA	J:265628
Cellular Component	GO:0031201	SNARE complex	IDA	J:137704
Cellular Component	GO:0031201	SNARE complex	IDA	J:137704
Cellular Component	GO:0031201	SNARE complex	ISO	J:206800
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Cellular Component	GO:0042588	zymogen granule	IDA	J:137704
Cellular Component	GO:0042588	zymogen granule	IDA	J:137704
Biological Process	GO:0097352	autophagosome maturation	ISO	J:164563
Biological Process	GO:0016240	autophagosome membrane docking	ISO	J:164563
Biological Process	GO:0006914	autophagy	IEA	J:60000
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:143718
Biological Process	GO:0051607	defense response to virus	IEA	J:60000
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:137704
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:137704
Biological Process	GO:0061025	membrane fusion	ISO	J:155856
Biological Process	GO:0070254	mucus secretion	IMP	J:195606
Biological Process	GO:0070254	mucus secretion	ISO	J:164563
Biological Process	GO:1903531	negative regulation of secretion by cell	ISO	J:164563
Biological Process	GO:1903595	positive regulation of histamine secretion by mast cell	ISO	J:164563
Biological Process	GO:1902278	positive regulation of pancreatic amylase secretion	IMP	J:137704
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:155856
Biological Process	GO:0030100	regulation of endocytosis	IMP	J:131844
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0035493	SNARE complex assembly	IDA	J:209479
Biological Process	GO:0035493	SNARE complex assembly	IBA	J:265628
Biological Process	GO:0006906	vesicle fusion	ISO	J:155856
Biological Process	GO:0006906	vesicle fusion	IBA	J:265628
Biological Process	GO:0006906	vesicle fusion	IMP	J:137704
Biological Process	GO:0006906	vesicle fusion	IMP	J:137704
Biological Process	GO:0016192	vesicle-mediated transport	ISO	J:155856
Biological Process	GO:0046718	viral entry into host cell	ISO	J:206800
Biological Process	GO:0070625	zymogen granule exocytosis	IMP	J:137704
Biological Process	GO:0070625	zymogen granule exocytosis	IMP	J:137704

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24