GO Annotations Graph

• Symbol: Nr1i2
• Name: nuclear receptor subfamily 1, group I, member 2
• ID: MGI:1337040

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:155856
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0016922	nuclear receptor binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:244975
Molecular Function	GO:0005515	protein binding	IPI	J:76833
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0045111	intermediate filament cytoskeleton	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005667	transcription regulator complex	EXP	J:320076
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:76833
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:146035
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:320074
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:320075
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0042178	xenobiotic catabolic process	ISO	J:164563
Biological Process	GO:0006805	xenobiotic metabolic process	ISO	J:164563
Biological Process	GO:0042908	xenobiotic transport	ISO	J:164563