GO Annotations Graph

• Symbol: Wdr1
• Name: WD repeat domain 1
• ID: MGI:1337100

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:53288
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051015	actin filament binding	ISO	J:182851
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:182851
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:53288
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0030864	cortical actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:211364
Biological Process	GO:0030042	actin filament depolymerization	IBA	J:265628
Biological Process	GO:0030043	actin filament fragmentation	IMP	J:233664
Biological Process	GO:0043297	apical junction assembly	ISO	J:164563
Biological Process	GO:0030865	cortical cytoskeleton organization	IMP	J:134092
Biological Process	GO:0042247	establishment of planar polarity of follicular epithelium	IMP	J:233664
Biological Process	GO:0040011	locomotion	IBA	J:265628
Biological Process	GO:0045199	maintenance of epithelial cell apical/basal polarity	ISO	J:164563
Biological Process	GO:0002446	neutrophil mediated immunity	IMP	J:134092
Biological Process	GO:1990266	neutrophil migration	IMP	J:134092
Biological Process	GO:0030220	platelet formation	IMP	J:134092
Biological Process	GO:0030836	positive regulation of actin filament depolymerization	IGI	J:211364
Biological Process	GO:0030834	regulation of actin filament depolymerization	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IMP	J:233664
Biological Process	GO:0048713	regulation of oligodendrocyte differentiation	ISO	J:182851
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	IMP	J:211364
Biological Process	GO:0045214	sarcomere organization	IBA	J:265628
Biological Process	GO:0045214	sarcomere organization	IMP	J:211364
Biological Process	GO:0007605	sensory perception of sound	ISO	J:53288