GO Annotations Graph

• Symbol: Bcl10
• Name: B cell leukemia/lymphoma 10
• ID: MGI:1337994

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050700	CARD domain binding	IPI	J:181290
Molecular Function	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	ISO	J:54311
Molecular Function	GO:0140296	general transcription initiation factor binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:116495
Molecular Function	GO:0019209	kinase activator activity	ISO	J:164563
Molecular Function	GO:0019209	kinase activator activity	IBA	J:265628
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:164563
Molecular Function	GO:0051059	NF-kappaB binding	IBA	J:265628
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:54313
Molecular Function	GO:0005515	protein binding	IPI	J:54313
Molecular Function	GO:0005515	protein binding	IPI	J:235268
Molecular Function	GO:0005515	protein binding	IPI	J:235268
Molecular Function	GO:0005515	protein binding	IPI	J:92393
Molecular Function	GO:0005515	protein binding	IPI	J:112532
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:55630
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:55630
Molecular Function	GO:0043422	protein kinase B binding	ISO	J:164563
Molecular Function	GO:0043422	protein kinase B binding	IBA	J:265628
Molecular Function	GO:0043621	protein self-association	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0032449	CBM complex	ISO	J:164563
Cellular Component	GO:0032449	CBM complex	IDA	J:181290
Cellular Component	GO:0032449	CBM complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:89322
Cellular Component	GO:0005737	cytoplasm	ISO	J:54311
Cellular Component	GO:0005881	cytoplasmic microtubule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:116495
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2730893
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0001772	immunological synapse	IDA	J:88285
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	IDA	J:89322
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0002096	polkadots	IDA	J:112532
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:54311
Biological Process	GO:0002250	adaptive immune response	ISO	J:164563
Biological Process	GO:0002250	adaptive immune response	IBA	J:265628
Biological Process	GO:0061760	antifungal innate immune response	IDA	J:181290
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0006915	apoptotic process	IEA	J:72247
Biological Process	GO:0001783	B cell apoptotic process	IDA	J:61738
Biological Process	GO:0008219	cell death	ISO	J:164563
Biological Process	GO:0006968	cellular defense response	IMP	J:67297
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IMP	J:67297
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	ISO	J:54312
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:67297
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0045576	mast cell activation	NAS	J:116420
Biological Process	GO:0002906	negative regulation of mature B cell apoptotic process	ISO	J:164563
Biological Process	GO:0001843	neural tube closure	IMP	J:67297
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:52071
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:61738
Biological Process	GO:0001819	positive regulation of cytokine production	IDA	J:181290
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1900119	positive regulation of execution phase of apoptosis	ISO	J:55630
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	IDA	J:61738
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0032757	positive regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IDA	J:181290
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:52071
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:55630
Biological Process	GO:0042327	positive regulation of phosphorylation	ISO	J:164563
Biological Process	GO:0031398	positive regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0050870	positive regulation of T cell activation	IMP	J:109545
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0051260	protein homooligomerization	ISO	J:164563
Biological Process	GO:0042981	regulation of apoptotic process	IEA	J:72247
Biological Process	GO:0050856	regulation of T cell receptor signaling pathway	IMP	J:109545
Biological Process	GO:0032094	response to food	ISO	J:164563
Biological Process	GO:0009620	response to fungus	IMP	J:111706
Biological Process	GO:0070231	T cell apoptotic process	IDA	J:61738
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0002224	toll-like receptor signaling pathway	ISO	J:164563