GO Annotations Graph

• Symbol: Gdf11
• Name: growth differentiation factor 11
• ID: MGI:1338027

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0008083	growth factor activity	IEA	J:60000
Molecular Function	GO:0008083	growth factor activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:116889
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:83365
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:201148
Biological Process	GO:0035881	amacrine cell differentiation	IDA	J:99244
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:94455
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:55879
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:55879
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:200671
Biological Process	GO:0048593	camera-type eye morphogenesis	IMP	J:99244
Biological Process	GO:0008283	cell population proliferation	IMP	J:94455
Biological Process	GO:0001656	metanephros development	IDA	J:83365
Biological Process	GO:1902870	negative regulation of amacrine cell differentiation	IDA	J:99244
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:94455
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0045665	negative regulation of neuron differentiation	IDA	J:99244
Biological Process	GO:0030182	neuron differentiation	IDA	J:99244
Biological Process	GO:0031016	pancreas development	IMP	J:94455
Biological Process	GO:0031016	pancreas development	IMP	J:94455
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA	J:265628
Biological Process	GO:0060021	roof of mouth development	IGI	J:201148
Biological Process	GO:0001501	skeletal system development	IGI	J:201148
Biological Process	GO:0001501	skeletal system development	IGI	J:201148
Biological Process	GO:0060395	SMAD protein signal transduction	IDA	J:116889
Biological Process	GO:0060395	SMAD protein signal transduction	ISO	J:164563
Biological Process	GO:0060395	SMAD protein signal transduction	IBA	J:265628
Biological Process	GO:0021512	spinal cord anterior/posterior patterning	IMP	J:119016
Biological Process	GO:0072560	type B pancreatic cell maturation	IMP	J:94455
Biological Process	GO:0001657	ureteric bud development	IMP	J:83365