GO Annotations Graph

• Symbol: Ovol2
• Name: ovo like zinc finger 2
• ID: MGI:1338039

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:213415
Molecular Function	GO:0003682	chromatin binding	IDA	J:213415
Molecular Function	GO:0003682	chromatin binding	IDA	J:213415
Molecular Function	GO:0003682	chromatin binding	IDA	J:213415
Molecular Function	GO:0003682	chromatin binding	IDA	J:213415
Molecular Function	GO:0003677	DNA binding	IDA	J:91895
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:213415
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISS	J:45546
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:281248
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:213415
Cellular Component	GO:0005634	nucleus	IDA	J:45546
Cellular Component	GO:0005634	nucleus	IDA	J:118154
Biological Process	GO:0001525	angiogenesis	IMP	J:132526
Biological Process	GO:0008283	cell population proliferation	IMP	J:106405
Biological Process	GO:0008283	cell population proliferation	IMP	J:106405
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	IDA	J:281248
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:106405
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	IMP	J:106405
Biological Process	GO:0060214	endocardium formation	IMP	J:132526
Biological Process	GO:0009913	epidermal cell differentiation	IMP	J:211311
Biological Process	GO:0009913	epidermal cell differentiation	IBA	J:265628
Biological Process	GO:0008544	epidermis development	IGI	J:213415
Biological Process	GO:0007507	heart development	IMP	J:106405
Biological Process	GO:0001947	heart looping	IMP	J:132526
Biological Process	GO:0060347	heart trabecula formation	IMP	J:132526
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:132526
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:106405
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	IMP	J:211311
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	IDA	J:281248
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:281248
Biological Process	GO:0045617	negative regulation of keratinocyte differentiation	ISO	J:164563
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	ISO	J:164563
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IGI	J:213415
Biological Process	GO:0010944	negative regulation of transcription by competitive promoter binding	ISO	J:164563
Biological Process	GO:0001755	neural crest cell migration	IMP	J:106405
Biological Process	GO:0001842	neural fold formation	IMP	J:106405
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:281248
Biological Process	GO:0045618	positive regulation of keratinocyte differentiation	IDA	J:213415
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0010837	regulation of keratinocyte proliferation	IMP	J:152595
Biological Process	GO:0010837	regulation of keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0060390	regulation of SMAD protein signal transduction	IDA	J:281248
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628