GO Annotations Graph

• Symbol: Klf5
• Name: Kruppel-like transcription factor 5
• ID: MGI:1338056

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:78275
Molecular Function	GO:0003677	DNA binding	ISS	J:97532
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:78275
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IGI	J:238742
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IGI	J:238742
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IGI	J:238742
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:238742
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0043426	MRF binding	IPI	J:238742
Molecular Function	GO:0043426	MRF binding	IPI	J:238742
Molecular Function	GO:0005515	protein binding	IPI	J:245256
Molecular Function	GO:0005515	protein binding	IPI	J:78275
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:238742
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:238742
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:238742
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:238742
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-442509
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9634438
Cellular Component	GO:0005634	nucleus	IDA	J:238742
Cellular Component	GO:0005634	nucleus	IDA	J:172214
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:238742
Biological Process	GO:0001525	angiogenesis	IMP	J:78275
Biological Process	GO:0099156	cell-cell signaling via exosome	ISO	J:164563
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0060576	intestinal epithelial cell development	IMP	J:194289
Biological Process	GO:0030033	microvillus assembly	IMP	J:78275
Biological Process	GO:0014908	myotube differentiation involved in skeletal muscle regeneration	IDA	J:238742
Biological Process	GO:0014908	myotube differentiation involved in skeletal muscle regeneration	IMP	J:238742
Biological Process	GO:0014908	myotube differentiation involved in skeletal muscle regeneration	IMP	J:238742
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:194289
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:78275
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IMP	J:182833
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:238742
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:238742
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:238742
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:238742
Biological Process	GO:0061586	positive regulation of transcription by transcription factor localization	IDA	J:238742
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IMP	J:238742
Biological Process	GO:0032534	regulation of microvillus assembly	IMP	J:194289
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:194289
Biological Process	GO:0014901	satellite cell activation involved in skeletal muscle regeneration	IMP	J:238742
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:178918
Biological Process	GO:0014816	skeletal muscle satellite cell differentiation	IMP	J:238742
Biological Process	GO:0043403	skeletal muscle tissue regeneration	IMP	J:238742