GO Annotations Graph

• Symbol: Pdpk1
• Name: 3-phosphoinositide dependent protein kinase 1
• ID: MGI:1338068

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	ISO	J:164563
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	ISO	J:155856
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	IDA	J:146938
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	IMP	J:136089
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	IDA	J:90081
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	IMP	J:90081
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	IMP	J:109010
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	IDA	J:53564
Molecular Function	GO:0004676	3-phosphoinositide-dependent protein kinase activity	IDA	J:53564
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005158	insulin receptor binding	ISO	J:155856
Molecular Function	GO:0019209	kinase activator activity	IDA	J:146938
Molecular Function	GO:0019209	kinase activator activity	IMP	J:136089
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016004	phospholipase activator activity	ISO	J:164563
Molecular Function	GO:0043274	phospholipase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:121227
Molecular Function	GO:0030295	protein kinase activator activity	IDA	J:90081
Molecular Function	GO:0030295	protein kinase activator activity	IMP	J:90081
Molecular Function	GO:0030295	protein kinase activator activity	IMP	J:109010
Molecular Function	GO:0030295	protein kinase activator activity	IDA	J:53564
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:85182
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:85182
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	IDA	J:187362
Biological Process	GO:0048041	focal adhesion assembly	ISO	J:155856
Biological Process	GO:0006972	hyperosmotic response	IDA	J:85182
Biological Process	GO:0008286	insulin receptor signaling pathway	IMP	J:136089
Biological Process	GO:0008286	insulin receptor signaling pathway	IDA	J:146938
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	IMP	J:327221
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	IDA	J:327177
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	IDA	J:307414
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	IMP	J:150014
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0034122	negative regulation of toll-like receptor signaling pathway	IMP	J:163291
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0010594	regulation of endothelial cell migration	IMP	J:134712
Biological Process	GO:0043304	regulation of mast cell degranulation	IMP	J:178435
Biological Process	GO:0007165	signal transduction	TAS	J:53564
Biological Process	GO:0003323	type B pancreatic cell development	IMP	J:153548