GO Annotations Graph

• Symbol: Ikbkg
• Name: inhibitor of kappaB kinase gamma
• ID: MGI:1338074

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	IPI	J:248213
Molecular Function	GO:0042802	identical protein binding	IPI	J:160776
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	ISO	J:164563
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	IBA	J:265628
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	IDA	J:128397
Molecular Function	GO:1990450	linear polyubiquitin binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:170302
Molecular Function	GO:0005515	protein binding	IPI	J:160362
Molecular Function	GO:0005515	protein binding	IPI	J:297482
Molecular Function	GO:0005515	protein binding	IPI	J:163158
Molecular Function	GO:0005515	protein binding	IPI	J:281166
Molecular Function	GO:0005515	protein binding	IPI	J:213524
Molecular Function	GO:0005515	protein binding	IPI	J:166021
Molecular Function	GO:0005515	protein binding	IPI	J:160776
Molecular Function	GO:0005515	protein binding	IPI	J:153758
Molecular Function	GO:0005515	protein binding	IPI	J:160329
Molecular Function	GO:0005515	protein binding	IPI	J:182492
Molecular Function	GO:0005515	protein binding	IPI	J:173147
Molecular Function	GO:0005515	protein binding	IPI	J:206842
Molecular Function	GO:0005515	protein binding	IPI	J:200492
Molecular Function	GO:0005515	protein binding	IPI	J:248213
Molecular Function	GO:0005515	protein binding	IPI	J:208236
Molecular Function	GO:0005515	protein binding	IPI	J:85253
Molecular Function	GO:0005515	protein binding	IPI	J:128397
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:1990459	transferrin receptor binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:87000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0008385	IkappaB kinase complex	ISO	J:155856
Cellular Component	GO:0008385	IkappaB kinase complex	IBA	J:265628
Cellular Component	GO:0008385	IkappaB kinase complex	ISO	J:205449
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Cellular Component	GO:0000151	ubiquitin ligase complex	ISO	J:164563
Biological Process	GO:0007250	activation of NF-kappaB-inducing kinase activity	IDA	J:87000
Biological Process	GO:0043276	anoikis	IMP	J:238448
Biological Process	GO:0001782	B cell homeostasis	IMP	J:79132
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0051650	establishment of vesicle localization	ISO	J:164563
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	IMP	J:198144
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:198144
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:128397
Biological Process	GO:0016239	positive regulation of macroautophagy	IMP	J:238448
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563