GO Annotations Graph

• Symbol: Cyfip1
• Name: cytoplasmic FMR1 interacting protein 1
• ID: MGI:1338801

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0005522	profilin binding	TAS	J:88449
Molecular Function	GO:0005515	protein binding	IPI	J:88664
Molecular Function	GO:0005515	protein binding	IPI	J:224720
Molecular Function	GO:0005515	protein binding	IPI	J:156046
Molecular Function	GO:0005515	protein binding	IPI	J:239183
Molecular Function	GO:0005515	protein binding	IPI	J:156046
Molecular Function	GO:0005515	protein binding	IPI	J:180006
Molecular Function	GO:0000340	RNA 7-methylguanosine cap binding	ISO	J:155856
Molecular Function	GO:0000340	RNA 7-methylguanosine cap binding	IBA	J:265628
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0045182	translation regulator activity	EXP	J:201819
Molecular Function	GO:0045182	translation regulator activity	IDA	J:201819
Molecular Function	GO:0045182	translation regulator activity	IPI	J:201819
Molecular Function	GO:0045182	translation regulator activity	IMP	J:201819
Molecular Function	GO:0045182	translation regulator activity	IMP	J:201819
Molecular Function	GO:0045182	translation regulator activity	IMP	J:201819
Molecular Function	GO:0045182	translation regulator activity	IDA	J:201819
Molecular Function	GO:0045182	translation regulator activity	IEP	J:201819
Molecular Function	GO:0045182	translation regulator activity	IPI	J:201819
Molecular Function	GO:0045182	translation regulator activity	IDA	J:201819
Cellular Component	GO:0044295	axonal growth cone	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0090724	central region of growth cone	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0044294	dendritic growth cone	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0032433	filopodium tip	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	IDA	J:88449
Cellular Component	GO:0005845	mRNA cap binding complex	IDA	J:156046
Cellular Component	GO:0043005	neuron projection	IDA	J:88664
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:88664
Cellular Component	GO:0090725	peripheral region of growth cone	ISO	J:155856
Cellular Component	GO:0098794	postsynapse	IDA	J:201819
Cellular Component	GO:0098794	postsynapse	IDA	J:201819
Cellular Component	GO:0031209	SCAR complex	ISO	J:164563
Cellular Component	GO:0031209	SCAR complex	IBA	J:265628
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0048675	axon extension	ISO	J:164563
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0000902	cell morphogenesis	IBA	J:265628
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:155856
Biological Process	GO:0050890	cognition	ISO	J:164563
Biological Process	GO:0097484	dendrite extension	IMP	J:239183
Biological Process	GO:0030032	lamellipodium assembly	IBA	J:265628
Biological Process	GO:0030032	lamellipodium assembly	IDA	J:88449
Biological Process	GO:0099563	modification of synaptic structure	IMP	J:201819
Biological Process	GO:0099563	modification of synaptic structure	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1903422	negative regulation of synaptic vesicle recycling	ISO	J:155856
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0031175	neuron projection development	IMP	J:239183
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	ISO	J:164563
Biological Process	GO:0045773	positive regulation of axon extension	ISO	J:155856
Biological Process	GO:0050772	positive regulation of axonogenesis	ISO	J:155856
Biological Process	GO:1900006	positive regulation of dendrite development	ISO	J:155856
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	IMP	J:239183
Biological Process	GO:1900029	positive regulation of ruffle assembly	ISO	J:155856
Biological Process	GO:0016601	Rac protein signal transduction	ISO	J:164563
Biological Process	GO:0030833	regulation of actin filament polymerization	IEA	J:72247
Biological Process	GO:0008360	regulation of cell shape	IEA	J:60000
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	IMP	J:201819
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	IDA	J:201819
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	IDA	J:201819
Biological Process	GO:0031641	regulation of myelination	ISO	J:155856
Biological Process	GO:0006417	regulation of translation	IMP	J:201819
Biological Process	GO:0006417	regulation of translation	IBA	J:265628
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IPI	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	EXP	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IDA	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IMP	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IEP	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IMP	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IDA	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IMP	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IPI	J:201819
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IDA	J:201819
Biological Process	GO:0051602	response to electrical stimulus	ISO	J:155856