GO Annotations Graph

• Symbol: Bmp10
• Name: bone morphogenetic protein 10
• ID: MGI:1338820

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0008083	growth factor activity	IEA	J:60000
Molecular Function	GO:0008083	growth factor activity	IEA	J:72247
Molecular Function	GO:0005179	hormone activity	ISO	J:164563
Molecular Function	GO:0033612	receptor serine/threonine kinase binding	ISO	J:164563
Molecular Function	GO:0031433	telethonin binding	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0030018	Z disc	ISO	J:164563
Biological Process	GO:0032924	activin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007512	adult heart development	IMP	J:116941
Biological Process	GO:0055009	atrial cardiac muscle tissue morphogenesis	IEP	J:53506
Biological Process	GO:0030509	BMP signaling pathway	IBA	J:265628
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:73065
Biological Process	GO:0060038	cardiac muscle cell proliferation	IMP	J:89476
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007507	heart development	IMP	J:89476
Biological Process	GO:0060347	heart trabecula formation	IMP	J:89476
Biological Process	GO:0001822	kidney development	IMP	J:231949
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	IMP	J:116941
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0010596	negative regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	IDA	J:116941
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IMP	J:119151
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	ISO	J:155856
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	ISO	J:164563
Biological Process	GO:0061036	positive regulation of cartilage development	IDA	J:219623
Biological Process	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	IGI	J:119151
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:186473
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IDA	J:116941
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA	J:265628
Biological Process	GO:0060298	positive regulation of sarcomere organization	ISO	J:164563
Biological Process	GO:0055117	regulation of cardiac muscle contraction	ISO	J:164563
Biological Process	GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	ISO	J:164563
Biological Process	GO:0045214	sarcomere organization	ISO	J:155856
Biological Process	GO:0060395	SMAD protein signal transduction	IBA	J:265628
Biological Process	GO:0055015	ventricular cardiac muscle cell development	IDA	J:116941
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IMP	J:119151
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IMP	J:89476