Bmpr1a GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Bmpr1a
bone morphogenetic protein receptor, type 1A
MGI:1338938

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0036122	BMP binding	IDA	J:299317
Molecular Function	GO:0036122	BMP binding	IDA	J:299322
Molecular Function	GO:0098821	BMP receptor activity	IMP	J:229306
Molecular Function	GO:0098821	BMP receptor activity	IMP	J:299435
Molecular Function	GO:0098821	BMP receptor activity	IDA	J:299322
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:228024
Molecular Function	GO:0005515	protein binding	IPI	J:93750
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAS	J:299435
Molecular Function	GO:0046332	SMAD binding	ISO	J:164563
Molecular Function	GO:0046332	SMAD binding	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0005025	transforming growth factor beta receptor activity, type I	IBA	J:265628
Molecular Function	GO:0004675	transmembrane receptor protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0004675	transmembrane receptor protein serine/threonine kinase activity	IEA	J:72247
Cellular Component	GO:0005901	caveola	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:268021
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:92179
Biological Process	GO:0060928	atrioventricular node cell development	IMP	J:142986
Biological Process	GO:0003171	atrioventricular valve development	IMP	J:75084
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:229306
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:164563
Biological Process	GO:0030509	BMP signaling pathway	IBA	J:265628
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:299435
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:101432
Biological Process	GO:0030509	BMP signaling pathway	IDA	J:42602
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:124681
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:119568
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:101432
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:109016
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:109016
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:124681
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:101432
Biological Process	GO:0061312	BMP signaling pathway involved in heart development	IMP	J:75084
Biological Process	GO:0061312	BMP signaling pathway involved in heart development	IC	J:89521
Biological Process	GO:0003161	cardiac conduction system development	IMP	J:111392
Biological Process	GO:0003215	cardiac right ventricle morphogenesis	IMP	J:89521
Biological Process	GO:0051216	cartilage development	IMP	J:97780
Biological Process	GO:0071773	cellular response to BMP stimulus	ISO	J:164563
Biological Process	GO:0071363	cellular response to growth factor stimulus	IBA	J:265628
Biological Process	GO:0021953	central nervous system neuron differentiation	IGI	J:93603
Biological Process	GO:0002062	chondrocyte differentiation	IDA	J:202818
Biological Process	GO:0048589	developmental growth	IMP	J:121318
Biological Process	GO:0048589	developmental growth	IMP	J:121318
Biological Process	GO:0035912	dorsal aorta morphogenesis	IMP	J:139945
Biological Process	GO:0009950	dorsal/ventral axis specification	IMP	J:84878
Biological Process	GO:0009953	dorsal/ventral pattern formation	IBA	J:265628
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:96964
Biological Process	GO:0007398	ectoderm development	IMP	J:92178
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:157085
Biological Process	GO:0048598	embryonic morphogenesis	IMP	J:97214
Biological Process	GO:0048568	embryonic organ development	IMP	J:75084
Biological Process	GO:0048568	embryonic organ development	IMP	J:121318
Biological Process	GO:0048568	embryonic organ development	IMP	J:121318
Biological Process	GO:0003272	endocardial cushion formation	IMP	J:104417
Biological Process	GO:0003203	endocardial cushion morphogenesis	IMP	J:75084
Biological Process	GO:0003203	endocardial cushion morphogenesis	IMP	J:89521
Biological Process	GO:0007492	endoderm development	IMP	J:92179
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:106392
Biological Process	GO:1905285	fibrous ring of heart morphogenesis	IMP	J:111392
Biological Process	GO:0007507	heart development	IMP	J:107396
Biological Process	GO:0007507	heart development	IMP	J:107396
Biological Process	GO:0060914	heart formation	IMP	J:119568
Biological Process	GO:0003007	heart morphogenesis	IMP	J:121318
Biological Process	GO:0003007	heart morphogenesis	IMP	J:121318
Biological Process	GO:0035137	hindlimb morphogenesis	IMP	J:107396
Biological Process	GO:0006955	immune response	ISO	J:164563
Biological Process	GO:0001701	in utero embryonic development	IMP	J:121318
Biological Process	GO:0001701	in utero embryonic development	IMP	J:121318
Biological Process	GO:0048368	lateral mesoderm development	IMP	J:119568
Biological Process	GO:0030324	lung development	IMP	J:106392
Biological Process	GO:0048382	mesendoderm development	IMP	J:92179
Biological Process	GO:0001707	mesoderm formation	IMP	J:124681
Biological Process	GO:0003183	mitral valve morphogenesis	IMP	J:111392
Biological Process	GO:0001880	Mullerian duct regression	IMP	J:89999
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:75084
Biological Process	GO:0051148	negative regulation of muscle cell differentiation	IMP	J:299435
Biological Process	GO:0050768	negative regulation of neurogenesis	IMP	J:124681
Biological Process	GO:0014912	negative regulation of smooth muscle cell migration	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IMP	J:121318
Biological Process	GO:0007399	nervous system development	IMP	J:121318
Biological Process	GO:0014032	neural crest cell development	IMP	J:153961
Biological Process	GO:0021998	neural plate mediolateral regionalization	IMP	J:119568
Biological Process	GO:0060896	neural plate pattern specification	IMP	J:119568
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:97214
Biological Process	GO:0001649	osteoblast differentiation	IDA	J:299402
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:89521
Biological Process	GO:0003148	outflow tract septum morphogenesis	IMP	J:89521
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:119568
Biological Process	GO:0048339	paraxial mesoderm development	IMP	J:119568
Biological Process	GO:0048352	paraxial mesoderm structural organization	IMP	J:119568
Biological Process	GO:0007389	pattern specification process	IMP	J:97214
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	IMP	J:89521
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0021983	pituitary gland development	IMP	J:121318
Biological Process	GO:0021983	pituitary gland development	IMP	J:121318
Biological Process	GO:0030501	positive regulation of bone mineralization	ISO	J:164563
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IMP	J:139945
Biological Process	GO:1904414	positive regulation of cardiac ventricle development	IMP	J:139945
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:106392
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:97214
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:97214
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:97214
Biological Process	GO:1902895	positive regulation of miRNA transcription	IDA	J:169047
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:139945
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:111392
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:152281
Biological Process	GO:0032915	positive regulation of transforming growth factor beta2 production	IMP	J:75084
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	IMP	J:139945
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	IMP	J:89521
Biological Process	GO:2000772	regulation of cellular senescence	IGI	J:190763
Biological Process	GO:0048378	regulation of lateral mesodermal cell fate specification	IGI	J:119568
Biological Process	GO:0060021	roof of mouth development	IMP	J:97214
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:124681
Biological Process	GO:0001756	somitogenesis	IMP	J:119568
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	IEA	J:72247
Biological Process	GO:0003186	tricuspid valve morphogenesis	IMP	J:111392
Biological Process	GO:0003223	ventricular compact myocardium morphogenesis	IMP	J:89521
Biological Process	GO:0060412	ventricular septum morphogenesis	IMP	J:75084
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	IMP	J:75084
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	IMP	J:89521

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24