GO Annotations Graph

• Symbol: Muc2
• Name: mucin 2
• ID: MGI:1339364

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1903135	cupric ion binding	ISO	J:164563
Molecular Function	GO:1903136	cuprous ion binding	ISO	J:164563
Molecular Function	GO:0005201	extracellular matrix structural constituent	IDA	J:332427
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:150756
Molecular Function	GO:0005515	protein binding	IPI	J:150765
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031012	extracellular matrix	IBA	J:265628
Cellular Component	GO:0031012	extracellular matrix	IDA	J:150765
Cellular Component	GO:0031012	extracellular matrix	IDA	J:92456
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0070702	inner mucus layer	IDA	J:142847
Cellular Component	GO:0070702	inner mucus layer	IDA	J:150756
Cellular Component	GO:0070701	mucus layer	ISO	J:155856
Cellular Component	GO:0070701	mucus layer	IDA	J:332427
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0070703	outer mucus layer	IDA	J:297095
Cellular Component	GO:0070703	outer mucus layer	IDA	J:150756
Cellular Component	GO:0070703	outer mucus layer	IDA	J:142847
Biological Process	GO:0006915	apoptotic process	IMP	J:75047
Biological Process	GO:0010273	detoxification of copper ion	ISO	J:164563
Biological Process	GO:0002068	glandular epithelial cell development	IMP	J:75047
Biological Process	GO:0048874	host-mediated regulation of intestinal microbiota composition	IDA	J:297095
Biological Process	GO:0030277	maintenance of gastrointestinal epithelium	IDA	J:297095
Biological Process	GO:0030277	maintenance of gastrointestinal epithelium	ISO	J:164563
Biological Process	GO:0030277	maintenance of gastrointestinal epithelium	IDA	J:332427
Biological Process	GO:0070254	mucus secretion	ISO	J:164563
Biological Process	GO:0070254	mucus secretion	IDA	J:332427
Biological Process	GO:0030336	negative regulation of cell migration	IMP	J:75047
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:75047
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:75047