GO Annotations Graph

• Symbol: Neurod1
• Name: neurogenic differentiation 1
• ID: MGI:1339708

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:172976
Molecular Function	GO:0003677	DNA binding	IDA	J:80902
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:210937
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0070888	E-box binding	IDA	J:87366
Molecular Function	GO:0070888	E-box binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:137207
Molecular Function	GO:0005515	protein binding	IPI	J:184710
Molecular Function	GO:0005515	protein binding	IPI	J:172919
Molecular Function	GO:0005515	protein binding	IPI	J:184001
Molecular Function	GO:0005515	protein binding	IPI	J:136893
Molecular Function	GO:0005515	protein binding	IPI	J:98743
Molecular Function	GO:0005515	protein binding	IPI	J:184001
Molecular Function	GO:0005515	protein binding	IPI	J:98743
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:210937
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:136893
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:105207
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:136893
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:120581
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:105207
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IC	J:80902
Cellular Component	GO:0005634	nucleus	IDA	J:136893
Cellular Component	GO:0005634	nucleus	IDA	J:75058
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Biological Process	GO:0035881	amacrine cell differentiation	IDA	J:74573
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:104896
Biological Process	GO:0061564	axon development	IBA	J:265628
Biological Process	GO:0043010	camera-type eye development	IGI	J:74573
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0045165	cell fate commitment	IGI	J:74573
Biological Process	GO:0071333	cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0021549	cerebellum development	IMP	J:74715
Biological Process	GO:0021542	dentate gyrus development	IMP	J:59932
Biological Process	GO:0021542	dentate gyrus development	IMP	J:74715
Biological Process	GO:0021542	dentate gyrus development	IGI	J:62118
Biological Process	GO:0048562	embryonic organ morphogenesis	IMP	J:43010
Biological Process	GO:0031018	endocrine pancreas development	IMP	J:43010
Biological Process	GO:0031018	endocrine pancreas development	IMP	J:59932
Biological Process	GO:0035883	enteroendocrine cell differentiation	IMP	J:43010
Biological Process	GO:0042593	glucose homeostasis	IMP	J:43010
Biological Process	GO:0030902	hindbrain development	IMP	J:104896
Biological Process	GO:0048839	inner ear development	IMP	J:66787
Biological Process	GO:0030073	insulin secretion	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	IDA	J:146992
Biological Process	GO:2000675	negative regulation of type B pancreatic cell apoptotic process	IMP	J:43010
Biological Process	GO:0007399	nervous system development	IEA	J:72247
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0048666	neuron development	IEA	J:72247
Biological Process	GO:0007263	nitric oxide mediated signal transduction	ISO	J:164563
Biological Process	GO:0006913	nucleocytoplasmic transport	ISO	J:155856
Biological Process	GO:0003326	pancreatic A cell fate commitment	IGI	J:129103
Biological Process	GO:0003329	pancreatic PP cell fate commitment	IGI	J:129103
Biological Process	GO:0043065	positive regulation of apoptotic process	IDA	J:172919
Biological Process	GO:0045597	positive regulation of cell differentiation	IDA	J:74573
Biological Process	GO:0045597	positive regulation of cell differentiation	IDA	J:172919
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:87366
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:87366
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:80902
Biological Process	GO:0045666	positive regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:172976
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:172976
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:172919
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:210937
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:89879
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:105207
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98743
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98743
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	ISO	J:164563
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	IDA	J:146992
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	IDA	J:146992
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0060730	regulation of intestinal epithelial structure maintenance	IDA	J:172919
Biological Process	GO:0045664	regulation of neuron differentiation	IGI	J:184001
Biological Process	GO:0045664	regulation of neuron differentiation	IGI	J:184001
Biological Process	GO:0045664	regulation of neuron differentiation	IGI	J:184001
Biological Process	GO:0009749	response to glucose	ISO	J:164563
Biological Process	GO:0007423	sensory organ development	IBA	J:265628
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:105207