GO Annotations Graph

• Symbol: Csf3
• Name: colony stimulating factor 3 (granulocyte)
• ID: MGI:1339751

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	NAS	J:114121
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0005130	granulocyte colony-stimulating factor receptor binding	IBA	J:265628
Molecular Function	GO:0005130	granulocyte colony-stimulating factor receptor binding	IPI	J:10454
Molecular Function	GO:0008083	growth factor activity	ISO	J:155856
Molecular Function	GO:0008083	growth factor activity	IBA	J:265628
Cellular Component	GO:0071682	endocytic vesicle lumen	TAS	Reactome:R-MMU-9707972
Cellular Component	GO:0071682	endocytic vesicle lumen	TAS	Reactome:R-MMU-9707979
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9674900
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9674908
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9674921
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9674931
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9674959
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9674973
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9676072
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9705471
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9707979
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0071345	cellular response to cytokine stimulus	ISO	J:164563
Biological Process	GO:0030851	granulocyte differentiation	NAS	J:114121
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:155856
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0030838	positive regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0045639	positive regulation of myeloid cell differentiation	IBA	J:265628
Biological Process	GO:0045639	positive regulation of myeloid cell differentiation	IGI	J:204177
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563