Csf1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Csf1
colony stimulating factor 1 (macrophage)
MGI:1339753

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005125	cytokine activity	ISO	J:73065
Molecular Function	GO:0008083	growth factor activity	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:245262
Molecular Function	GO:0005157	macrophage colony-stimulating factor receptor binding	IPI	J:145880
Molecular Function	GO:0005157	macrophage colony-stimulating factor receptor binding	IPI	J:7888
Molecular Function	GO:0005515	protein binding	IPI	J:117509
Molecular Function	GO:0005515	protein binding	IPI	J:245355
Molecular Function	GO:0005515	protein binding	IPI	J:145880
Molecular Function	GO:0005515	protein binding	IPI	J:245262
Molecular Function	GO:0005515	protein binding	IPI	J:117509
Molecular Function	GO:0005515	protein binding	IPI	J:218799
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:145880
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:1990682	CSF1-CSF1R complex	IDA	J:145880
Cellular Component	GO:0005576	extracellular region	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9680646
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9680703
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9680705
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9680706
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9682158
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9682182
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9682572
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9763891
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9763892
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9763901
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9763903
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9764150
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9817994
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9818009
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0060444	branching involved in mammary gland duct morphogenesis	IMP	J:110688
Biological Process	GO:0008283	cell population proliferation	ISO	J:155856
Biological Process	GO:0003006	developmental process involved in reproduction	IMP	J:105388
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IMP	J:41240
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IMP	J:41240
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IMP	J:41240
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0038145	macrophage colony-stimulating factor signaling pathway	IDA	J:145880
Biological Process	GO:0030225	macrophage differentiation	ISO	J:155856
Biological Process	GO:0030225	macrophage differentiation	IMP	J:41240
Biological Process	GO:0061519	macrophage homeostasis	IMP	J:41240
Biological Process	GO:0061519	macrophage homeostasis	IMP	J:41240
Biological Process	GO:0061519	macrophage homeostasis	IMP	J:41240
Biological Process	GO:0060763	mammary duct terminal end bud growth	IMP	J:110688
Biological Process	GO:0060611	mammary gland fat development	IMP	J:110688
Biological Process	GO:0060611	mammary gland fat development	IMP	J:110688
Biological Process	GO:0061518	microglial cell proliferation	IGI	J:269538
Biological Process	GO:0030224	monocyte differentiation	IMP	J:41240
Biological Process	GO:0035702	monocyte homeostasis	IMP	J:41240
Biological Process	GO:0035702	monocyte homeostasis	IMP	J:41240
Biological Process	GO:0035702	monocyte homeostasis	IMP	J:41240
Biological Process	GO:0097529	myeloid leukocyte migration	IGI	J:114609
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:164563
Biological Process	GO:0001780	neutrophil homeostasis	IMP	J:41240
Biological Process	GO:0001780	neutrophil homeostasis	IMP	J:41240
Biological Process	GO:0001780	neutrophil homeostasis	IMP	J:41240
Biological Process	GO:0042476	odontogenesis	ISO	J:155856
Biological Process	GO:0001503	ossification	ISO	J:155856
Biological Process	GO:0030316	osteoclast differentiation	ISO	J:164563
Biological Process	GO:0030316	osteoclast differentiation	ISO	J:155856
Biological Process	GO:0030316	osteoclast differentiation	IBA	J:265628
Biological Process	GO:0030316	osteoclast differentiation	IGI	J:114609
Biological Process	GO:0030316	osteoclast differentiation	IDA	J:145836
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:41240
Biological Process	GO:0002158	osteoclast proliferation	IDA	J:193006
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:73065
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	IGI	J:114609
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:273531
Biological Process	GO:0002687	positive regulation of leukocyte migration	IGI	J:114609
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	ISO	J:164563
Biological Process	GO:1902228	positive regulation of macrophage colony-stimulating factor signaling pathway	ISO	J:164563
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	ISO	J:164563
Biological Process	GO:0045651	positive regulation of macrophage differentiation	ISO	J:164563
Biological Process	GO:0045651	positive regulation of macrophage differentiation	IBA	J:265628
Biological Process	GO:0045651	positive regulation of macrophage differentiation	IMP	J:41240
Biological Process	GO:1905523	positive regulation of macrophage migration	ISO	J:164563
Biological Process	GO:0120041	positive regulation of macrophage proliferation	ISO	J:155856
Biological Process	GO:1904141	positive regulation of microglial cell migration	ISO	J:164563
Biological Process	GO:0045657	positive regulation of monocyte differentiation	IMP	J:41240
Biological Process	GO:0071677	positive regulation of mononuclear cell migration	ISO	J:155856
Biological Process	GO:0032946	positive regulation of mononuclear cell proliferation	ISO	J:164563
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:84815
Biological Process	GO:0042488	positive regulation of odontogenesis of dentin-containing tooth	IMP	J:84815
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	ISO	J:164563
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IGI	J:166692
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IGI	J:114609
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IMP	J:41240
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IDA	J:95992
Biological Process	GO:0045860	positive regulation of protein kinase activity	IGI	J:114609
Biological Process	GO:0051247	positive regulation of protein metabolic process	ISO	J:164563
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	IDA	J:114609
Biological Process	GO:0007265	Ras protein signal transduction	IDA	J:114609
Biological Process	GO:0030278	regulation of ossification	IMP	J:84815
Biological Process	GO:0002931	response to ischemia	ISO	J:164563
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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