GO Annotations Graph

• Symbol: Crlf1
• Name: cytokine receptor-like factor 1
• ID: MGI:1340030

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005127	ciliary neurotrophic factor receptor binding	ISO	J:164563
Molecular Function	GO:0005127	ciliary neurotrophic factor receptor binding	TAS	J:85998
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0019955	cytokine binding	ISO	J:164563
Molecular Function	GO:0019955	cytokine binding	IBA	J:265628
Molecular Function	GO:0004896	cytokine receptor activity	IBA	J:265628
Cellular Component	GO:0097058	CRLF-CLCF1 complex	ISO	J:164563
Cellular Component	GO:0097058	CRLF-CLCF1 complex	TAS	J:85998
Cellular Component	GO:0097058	CRLF-CLCF1 complex	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IBA	J:265628
Biological Process	GO:2000672	negative regulation of motor neuron apoptotic process	IMP	J:85998
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	IBA	J:265628
Biological Process	GO:0001657	ureteric bud development	IEP	J:112220