GO Annotations Graph

• Symbol: Sgk1
• Name: serum/glucocorticoid regulated kinase 1
• ID: MGI:1340062

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043423	3-phosphoinositide-dependent protein kinase binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0015459	potassium channel regulator activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:248219
Molecular Function	GO:0005515	protein binding	IPI	J:115432
Molecular Function	GO:0004672	protein kinase activity	IDA	J:93432
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004712	protein serine/threonine/tyrosine kinase activity	ISO	J:199676
Molecular Function	GO:0048156	tau protein binding	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9022765
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:1904045	cellular response to aldosterone	IDA	J:160934
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:73065
Biological Process	GO:0006974	DNA damage response	IDA	J:93432
Biological Process	GO:0043402	glucocorticoid mediated signaling pathway	ISO	J:155856
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:155856
Biological Process	GO:0007616	long-term memory	ISO	J:155856
Biological Process	GO:0007019	microtubule depolymerization	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0031115	negative regulation of microtubule polymerization	ISO	J:155856
Biological Process	GO:0048812	neuron projection morphogenesis	ISO	J:155856
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:155856
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:155856
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0010765	positive regulation of sodium ion transport	ISO	J:73065
Biological Process	GO:0006468	protein phosphorylation	IDA	J:93432
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:155856
Biological Process	GO:0032880	regulation of protein localization	ISO	J:73065
Biological Process	GO:0008542	visual learning	ISO	J:155856