GO Annotations Graph

• Symbol: Tnks
• Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
• ID: MGI:1341087

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016757	glycosyltransferase activity	IEA	J:60000
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	IBA	J:265628
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	ISO	J:73065
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0016779	nucleotidyltransferase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:201692
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0097431	mitotic spindle pole	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005643	nuclear pore	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0051028	mRNA transport	IEA	J:60000
Biological Process	GO:1904908	negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric	ISO	J:164563
Biological Process	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	ISO	J:164563
Biological Process	GO:1904743	negative regulation of telomeric DNA binding	ISO	J:164563
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:114505
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	ISO	J:114505
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0051973	positive regulation of telomerase activity	ISO	J:164563
Biological Process	GO:1904355	positive regulation of telomere capping	ISO	J:164563
Biological Process	GO:1904355	positive regulation of telomere capping	IBA	J:265628
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0070213	protein auto-ADP-ribosylation	ISO	J:164563
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	ISO	J:164563
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	IBA	J:265628
Biological Process	GO:0070212	protein poly-ADP-ribosylation	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0051225	spindle assembly	IEA	J:72247
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:72247