GO Annotations Graph

• Symbol: Parp2
• Name: poly (ADP-ribose) polymerase family, member 2
• ID: MGI:1341112

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0016757	glycosyltransferase activity	IEA	J:60000
Molecular Function	GO:0140294	NAD DNA ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	IDA	J:78954
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	IDA	J:55622
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0031491	nucleosome binding	ISO	J:164563
Molecular Function	GO:0016779	nucleotidyltransferase activity	IEA	J:60000
Molecular Function	GO:0072572	poly-ADP-D-ribose binding	ISO	J:164563
Molecular Function	GO:0160004	poly-ADP-D-ribose modification-dependent protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:94965
Molecular Function	GO:0005515	protein binding	IPI	J:77259
Molecular Function	GO:0005515	protein binding	IPI	J:77259
Molecular Function	GO:0005515	protein binding	IPI	J:77259
Molecular Function	GO:0005515	protein binding	IPI	J:77259
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005730	nucleolus	IDA	J:94965
Cellular Component	GO:0005730	nucleolus	ISO	J:73065
Cellular Component	GO:0005654	nucleoplasm	ISO	J:73065
Cellular Component	GO:0005654	nucleoplasm	IDA	J:94965
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:78954
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Biological Process	GO:0006284	base-excision repair	IMP	J:77259
Biological Process	GO:0046697	decidualization	IMP	J:311744
Biological Process	GO:0030592	DNA ADP-ribosylation	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0006281	DNA repair	TAS	J:78954
Biological Process	GO:0140861	DNA repair-dependent chromatin remodeling	ISO	J:164563
Biological Process	GO:0006302	double-strand break repair	ISO	J:164563
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IDA	J:78954
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:155856
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0070213	protein auto-ADP-ribosylation	ISO	J:164563
Biological Process	GO:0070212	protein poly-ADP-ribosylation	ISO	J:164563