GO Annotations Graph

• Symbol: Gldc
• Name: glycine decarboxylase
• ID: MGI:1341155

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0016594	glycine binding	ISO	J:155856
Molecular Function	GO:0016594	glycine binding	IBA	J:265628
Molecular Function	GO:0004375	glycine dehydrogenase (decarboxylating) activity	ISO	J:164563
Molecular Function	GO:0004375	glycine dehydrogenase (decarboxylating) activity	ISO	J:155856
Molecular Function	GO:0004375	glycine dehydrogenase (decarboxylating) activity	IBA	J:265628
Molecular Function	GO:0004375	glycine dehydrogenase (decarboxylating) activity	ISO	J:73065
Molecular Function	GO:0004375	glycine dehydrogenase (decarboxylating) activity	ISO	J:53416
Molecular Function	GO:0016829	lyase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:73065
Molecular Function	GO:0030170	pyridoxal phosphate binding	ISO	J:155856
Molecular Function	GO:0030170	pyridoxal phosphate binding	IBA	J:265628
Cellular Component	GO:0005960	glycine cleavage complex	ISO	J:155856
Cellular Component	GO:0005960	glycine cleavage complex	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	ISO	J:73065
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0006520	amino acid metabolic process	IEA	J:72247
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0006546	glycine catabolic process	ISO	J:164563
Biological Process	GO:0019464	glycine decarboxylation via glycine cleavage system	ISO	J:155856
Biological Process	GO:0019464	glycine decarboxylation via glycine cleavage system	IBA	J:265628
Biological Process	GO:0019464	glycine decarboxylation via glycine cleavage system	ISO	J:73065
Biological Process	GO:0006544	glycine metabolic process	IEA	J:72247
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:155856