GO Annotations Graph

• Symbol: Trpv1
• Name: transient receptor potential cation channel, subfamily V, member 1
• ID: MGI:1341787

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005262	calcium channel activity	IBA	J:265628
Molecular Function	GO:0005262	calcium channel activity	IMP	J:61534
Molecular Function	GO:0005262	calcium channel activity	IMP	J:127256
Molecular Function	GO:0015278	calcium-release channel activity	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	ISO	J:155856
Molecular Function	GO:0017081	chloride channel regulator activity	ISO	J:155856
Molecular Function	GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	ISO	J:155856
Molecular Function	GO:0005230	extracellular ligand-gated monoatomic ion channel activity	ISO	J:155856
Molecular Function	GO:0005230	extracellular ligand-gated monoatomic ion channel activity	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:245308
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005261	monoatomic cation channel activity	ISO	J:155856
Molecular Function	GO:0005261	monoatomic cation channel activity	ISA	J:98288
Molecular Function	GO:0008324	monoatomic cation transmembrane transporter activity	ISO	J:73065
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:155856
Molecular Function	GO:0051219	phosphoprotein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:219559
Molecular Function	GO:0005515	protein binding	IPI	J:145300
Molecular Function	GO:0097603	temperature-gated ion channel activity	IMP	J:191353
Molecular Function	GO:0097603	temperature-gated ion channel activity	IDA	J:145300
Molecular Function	GO:0004888	transmembrane signaling receptor activity	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:73065
Cellular Component	GO:0016020	membrane	ISA	J:98288
Cellular Component	GO:0016020	membrane	ISO	J:73065
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:111371
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:145300
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0048266	behavioral response to pain	IMP	J:133326
Biological Process	GO:0048266	behavioral response to pain	IDA	J:145300
Biological Process	GO:0048266	behavioral response to pain	IMP	J:127256
Biological Process	GO:0098703	calcium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0098703	calcium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0098703	calcium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	IDA	J:119083
Biological Process	GO:0006816	calcium ion transport	IMP	J:127256
Biological Process	GO:0042637	catagen	IMP	J:110694
Biological Process	GO:0071468	cellular response to acidic pH	ISO	J:164563
Biological Process	GO:0071468	cellular response to acidic pH	ISO	J:155856
Biological Process	GO:0071312	cellular response to alkaloid	ISO	J:155856
Biological Process	GO:0071318	cellular response to ATP	ISO	J:155856
Biological Process	GO:0071345	cellular response to cytokine stimulus	ISO	J:155856
Biological Process	GO:0034605	cellular response to heat	ISO	J:155856
Biological Process	GO:0034605	cellular response to heat	ISO	J:164563
Biological Process	GO:0050968	detection of chemical stimulus involved in sensory perception of pain	IDA	J:135245
Biological Process	GO:0050968	detection of chemical stimulus involved in sensory perception of pain	IMP	J:135695
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	IMP	J:191353
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	IGI	J:191353
Biological Process	GO:0050960	detection of temperature stimulus involved in thermoception	IDA	J:145300
Biological Process	GO:0002024	diet induced thermogenesis	IMP	J:78707
Biological Process	GO:0001660	fever generation	IMP	J:104828
Biological Process	GO:0014047	glutamate secretion	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IMP	J:78707
Biological Process	GO:0001774	microglial cell activation	ISO	J:155856
Biological Process	GO:0006812	monoatomic cation transport	ISA	J:98288
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IMP	J:191353
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0090212	negative regulation of establishment of blood-brain barrier	ISO	J:155856
Biological Process	GO:0010459	negative regulation of heart rate	ISO	J:155856
Biological Process	GO:0010917	negative regulation of mitochondrial membrane potential	ISO	J:155856
Biological Process	GO:0003085	negative regulation of systemic arterial blood pressure	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:188264
Biological Process	GO:0002790	peptide secretion	IMP	J:131042
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0060454	positive regulation of gastric acid secretion	ISO	J:155856
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	ISO	J:155856
Biological Process	GO:0051289	protein homotetramerization	ISO	J:155856
Biological Process	GO:1901594	response to capsazepine	ISO	J:155856
Biological Process	GO:1901594	response to capsazepine	ISO	J:164563
Biological Process	GO:0009408	response to heat	ISO	J:73065
Biological Process	GO:0009408	response to heat	IMP	J:61534
Biological Process	GO:0010243	response to organonitrogen compound	IMP	J:127256
Biological Process	GO:0048265	response to pain	IDA	J:135245
Biological Process	GO:0048265	response to pain	IMP	J:135695
Biological Process	GO:0009268	response to pH	IMP	J:61534
Biological Process	GO:0009268	response to pH	ISO	J:73065
Biological Process	GO:0050954	sensory perception of mechanical stimulus	IMP	J:78707
Biological Process	GO:0019233	sensory perception of pain	IMP	J:61534
Biological Process	GO:0060083	smooth muscle contraction involved in micturition	IMP	J:78707
Biological Process	GO:0001659	temperature homeostasis	IMP	J:61534
Biological Process	GO:0050955	thermoception	ISO	MGI:MGI:2156083
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0014832	urinary bladder smooth muscle contraction	IMP	J:78707