GO Annotations Graph

• Symbol: Rps6ka2
• Name: ribosomal protein S6 kinase, polypeptide 2
• ID: MGI:1342290

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:94781
Molecular Function	GO:0004672	protein kinase activity	IDA	J:94781
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAS	Reactome:R-NUL-3876071
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:16744
Molecular Function	GO:0004712	protein serine/threonine/tyrosine kinase activity	ISO	J:199676
Molecular Function	GO:0004711	ribosomal protein S6 kinase activity	IBA	J:265628
Molecular Function	GO:0004711	ribosomal protein S6 kinase activity	IDA	J:121666
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:94781
Cellular Component	GO:0072687	meiotic spindle	IDA	J:94781
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-3876071
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005819	spindle	IDA	J:93217
Biological Process	GO:0002035	brain renin-angiotensin system	IDA	J:121666
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	IDA	J:121666
Biological Process	GO:0071322	cellular response to carbohydrate stimulus	IDA	J:121666
Biological Process	GO:0060047	heart contraction	IDA	J:121666
Biological Process	GO:0007507	heart development	IDA	J:121666
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0045786	negative regulation of cell cycle	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045835	negative regulation of meiotic nuclear division	IDA	J:94781
Biological Process	GO:0001556	oocyte maturation	IDA	J:94781
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IDA	J:16744
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:121666
Biological Process	GO:0006468	protein phosphorylation	IDA	J:94781
Biological Process	GO:0070613	regulation of protein processing	IMP	J:121666