Ruvbl2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ruvbl2
RuvB-like AAA ATPase 2
MGI:1342299

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043531	ADP binding	IDA	J:227386
Molecular Function	GO:0005524	ATP binding	IDA	J:227386
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	IEA	J:72247
Molecular Function	GO:0051117	ATPase binding	IPI	J:227386
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:164563
Molecular Function	GO:0003678	DNA helicase activity	ISO	J:164563
Molecular Function	GO:0003678	DNA helicase activity	IBA	J:265628
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0140585	promoter-enhancer loop anchoring activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:165255
Molecular Function	GO:0005515	protein binding	IPI	J:227386
Molecular Function	GO:0005515	protein binding	IPI	J:227386
Molecular Function	GO:0005515	protein binding	IPI	J:160776
Molecular Function	GO:0005515	protein binding	IPI	J:227386
Molecular Function	GO:0005515	protein binding	IPI	J:265009
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:227386
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0017025	TBP-class protein binding	ISO	J:164563
Molecular Function	GO:0001094	TFIID-class transcription factor complex binding	IPI	J:227386
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0000791	euchromatin	ISO	J:164563
Cellular Component	GO:0031011	Ino80 complex	ISO	J:164563
Cellular Component	GO:0031011	Ino80 complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0071339	MLL1 complex	ISO	J:164563
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	ISO	J:164563
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0000786	nucleosome	ISO	J:164563
Cellular Component	GO:0000786	nucleosome	NAS	J:320032
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0101031	protein folding chaperone complex	ISO	J:164563
Cellular Component	GO:0097255	R2TP complex	ISO	J:164563
Cellular Component	GO:0097255	R2TP complex	IBA	J:265628
Cellular Component	GO:1990904	ribonucleoprotein complex	IDA	J:148546
Cellular Component	GO:1990062	RPAP3/R2TP/prefoldin-like complex	ISO	J:164563
Cellular Component	GO:0000812	Swr1 complex	ISO	J:164563
Cellular Component	GO:0000812	Swr1 complex	IBA	J:265628
Biological Process	GO:0000492	box C/D snoRNP assembly	IBA	J:265628
Biological Process	GO:0071392	cellular response to estradiol stimulus	ISO	J:164563
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0071169	establishment of protein localization to chromatin	ISO	J:164563
Biological Process	GO:0016573	histone acetylation	NAS	J:320265
Biological Process	GO:0016573	histone acetylation	IBA	J:265628
Biological Process	GO:0043968	histone H2A acetylation	ISO	J:164563
Biological Process	GO:0043967	histone H4 acetylation	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	IDA	J:221224
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:319957
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:1904507	positive regulation of telomere maintenance in response to DNA damage	IMP	J:221224
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0042981	regulation of apoptotic process	NAS	J:320265
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0033044	regulation of chromosome organization	ISO	J:164563
Biological Process	GO:0006282	regulation of DNA repair	IDA	J:221224
Biological Process	GO:0006275	regulation of DNA replication	ISO	J:164563
Biological Process	GO:0060382	regulation of DNA strand elongation	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	NAS	J:320032
Biological Process	GO:2000779	regulation of double-strand break repair	NAS	J:320265
Biological Process	GO:0045995	regulation of embryonic development	IMP	J:221224
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000723	telomere maintenance	IMP	J:221224

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24