GO Annotations Graph

• Symbol: Ppef2
• Name: protein phosphatase, EF hand calcium-binding domain 2
• ID: MGI:1342304

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0030544	Hsp70 protein binding	ISO	J:164563
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:164563
Molecular Function	GO:0051879	Hsp90 protein binding	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0005506	iron ion binding	IEA	J:72247
Molecular Function	GO:0030145	manganese ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ISO	J:164563
Molecular Function	GO:0017018	myosin phosphatase activity	IEA	J:72245
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:72247
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IBA	J:265628
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	ISS	J:43592
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0050906	detection of stimulus involved in sensory perception	IEA	J:72247
Biological Process	GO:0043409	negative regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0043409	negative regulation of MAPK cascade	IBA	J:265628
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0050896	response to stimulus	IEA	J:60000
Biological Process	GO:0007601	visual perception	IEA	J:60000