GO Annotations Graph

• Symbol: Ndufs4
• Name: NADH:ubiquinone oxidoreductase core subunit S4
• ID: MGI:1343135

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	ISO	J:164563
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	ISO	J:164563
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	IMP	J:271477
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	IMP	J:232864
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	IMP	J:134334
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	IDA	J:62752
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	IEA	J:60000
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	ISO	J:164563
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	IBA	J:265628
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	IDA	J:206222
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	IDA	J:134334
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	IDA	J:62752
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:134334
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0070469	respirasome	IEA	J:60000
Biological Process	GO:0030534	adult behavior	IMP	J:260020
Biological Process	GO:0007628	adult walking behavior	IMP	J:227501
Biological Process	GO:0009060	aerobic respiration	NAS	J:320063
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0007420	brain development	IMP	J:255567
Biological Process	GO:0045333	cellular respiration	ISO	J:164563
Biological Process	GO:0071453	cellular response to oxygen levels	IMP	J:266510
Biological Process	GO:0050890	cognition	IMP	J:260020
Biological Process	GO:0042417	dopamine metabolic process	IMP	J:260020
Biological Process	GO:0022900	electron transport chain	IEA	J:72247
Biological Process	GO:0006954	inflammatory response	IMP	J:220851
Biological Process	GO:0045087	innate immune response	IMP	J:220851
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	ISO	J:164563
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	IMP	J:134334
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:220851
Biological Process	GO:0048666	neuron development	IMP	J:227501
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:0042776	proton motive force-driven mitochondrial ATP synthesis	NAS	J:320063
Biological Process	GO:0036343	psychomotor behavior	IMP	J:260020
Biological Process	GO:0072593	reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:271477
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	IMP	J:232864
Biological Process	GO:0001932	regulation of protein phosphorylation	ISO	J:67810
Biological Process	GO:0022904	respiratory electron transport chain	IMP	J:270767
Biological Process	GO:0003016	respiratory system process	IMP	J:260020
Biological Process	GO:0051591	response to cAMP	ISO	J:164563
Biological Process	GO:0014876	response to injury involved in regulation of muscle adaptation	IMP	J:271477
Biological Process	GO:0007605	sensory perception of sound	IMP	J:134334
Biological Process	GO:0006099	tricarboxylic acid cycle	TAS	J:270767
Biological Process	GO:0007601	visual perception	IMP	J:220851