GO Annotations Graph

• Symbol: Klk8
• Name: kallikrein related-peptidase 8
• ID: MGI:1343327

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IDA	J:274112
Molecular Function	GO:0008233	peptidase activity	IMP	J:274112
Molecular Function	GO:0004252	serine-type endopeptidase activity	IDA	J:130007
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004252	serine-type endopeptidase activity	IDA	J:130015
Molecular Function	GO:0008236	serine-type peptidase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:164861
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IDA	J:130015
Cellular Component	GO:0097180	serine protease inhibitor complex	ISO	J:164563
Biological Process	GO:0008219	cell death	IMP	J:128299
Biological Process	GO:0043616	keratinocyte proliferation	IMP	J:120872
Biological Process	GO:0007613	memory	IMP	J:130005
Biological Process	GO:0007613	memory	IBA	J:265628
Biological Process	GO:0048681	negative regulation of axon regeneration	IMP	J:128299
Biological Process	GO:0031642	negative regulation of myelination	IMP	J:128299
Biological Process	GO:0048812	neuron projection morphogenesis	IDA	J:130010
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0006508	proteolysis	IEA	J:72247
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0050807	regulation of synapse organization	IMP	J:68653
Biological Process	GO:0009611	response to wounding	IDA	J:130032
Biological Process	GO:0009611	response to wounding	IDA	J:130012
Biological Process	GO:0009611	response to wounding	IDA	J:130013
Biological Process	GO:0050808	synapse organization	IMP	J:106989