GO Annotations Graph

• Symbol: Dand5
• Name: DAN domain family member 5, BMP antagonist
• ID: MGI:1344365

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016015	morphogen activity	IMP	J:93051
Molecular Function	GO:0016015	morphogen activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:93051
Cellular Component	GO:0005576	extracellular region	NAS	J:93051
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0003283	atrial septum development	IMP	J:93051
Biological Process	GO:0061371	determination of heart left/right asymmetry	IMP	J:93051
Biological Process	GO:0061371	determination of heart left/right asymmetry	IBA	J:265628
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	IMP	J:93051
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:93051
Biological Process	GO:0007368	determination of left/right symmetry	IGI	J:93051
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IDA	J:93051
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	IDA	J:93051
Biological Process	GO:1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	IBA	J:265628
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IGI	J:93015
Biological Process	GO:1900164	nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	NAS	J:182383
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	IDA	J:54640
Biological Process	GO:0035582	sequestering of BMP in extracellular matrix	IBA	J:265628
Biological Process	GO:0038101	sequestering of nodal from receptor via nodal binding	IDA	J:93051
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IBA	J:265628
Biological Process	GO:0003281	ventricular septum development	IMP	J:93051