GO Annotations Graph

• Symbol: Prkra
• Name: protein kinase, interferon inducible double stranded RNA dependent activator
• ID: MGI:1344375

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003725	double-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	IBA	J:265628
Molecular Function	GO:0008047	enzyme activator activity	IEA	J:72247
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0070883	pre-miRNA binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:148059
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0035197	siRNA binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:108297
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0016442	RISC complex	IBA	J:265628
Cellular Component	GO:0070578	RISC-loading complex	ISO	J:164563
Cellular Component	GO:0070578	RISC-loading complex	IBA	J:265628
Biological Process	GO:0034599	cellular response to oxidative stress	IDA	J:55431
Biological Process	GO:0043583	ear development	IMP	J:223062
Biological Process	GO:0043583	ear development	IMP	J:223062
Biological Process	GO:0043583	ear development	IMP	J:223062
Biological Process	GO:0043583	ear development	IMP	J:223062
Biological Process	GO:0042474	middle ear morphogenesis	IMP	J:108297
Biological Process	GO:0035196	miRNA processing	ISO	J:164563
Biological Process	GO:0042473	outer ear morphogenesis	IMP	J:108297
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	IDA	J:78899
Biological Process	GO:0031054	pre-miRNA processing	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:55431
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0070920	regulation of regulatory ncRNA processing	IBA	J:265628
Biological Process	GO:0031047	RNA-mediated gene silencing	IEA	J:60000
Biological Process	GO:0030422	siRNA processing	ISO	J:164563
Biological Process	GO:0030422	siRNA processing	IBA	J:265628
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:108297