GO Annotations Graph

• Symbol: Agr2
• Name: anterior gradient 2
• ID: MGI:1344405

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0002162	dystroglycan binding	ISO	J:164563
Molecular Function	GO:0002162	dystroglycan binding	IBA	J:265628
Molecular Function	GO:0005154	epidermal growth factor receptor binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:304730
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:304730
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:148339
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Biological Process	GO:0060326	cell chemotaxis	ISO	J:304730
Biological Process	GO:0048546	digestive tract morphogenesis	IMP	J:220492
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	ISO	J:304730
Biological Process	GO:0006954	inflammatory response	IMP	J:304730
Biological Process	GO:0060480	lung goblet cell differentiation	IDA	J:185603
Biological Process	GO:0070254	mucus secretion	IMP	J:148339
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:0060548	negative regulation of cell death	IBA	J:265628
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0048639	positive regulation of developmental growth	IMP	J:220492
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:1903896	positive regulation of IRE1-mediated unfolded protein response	ISO	J:164563
Biological Process	GO:1903899	positive regulation of PERK-mediated unfolded protein response	ISO	J:164563
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0034975	protein folding in endoplasmic reticulum	ISO	J:304730