GO Annotations Graph

• Symbol: Ash2l
• Name: ASH2 like histone lysine methyltransferase complex subunit
• ID: MGI:1344416

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	TAS	J:185349
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:248275
Molecular Function	GO:0005515	protein binding	IPI	J:171270
Molecular Function	GO:0005515	protein binding	IPI	J:247433
Molecular Function	GO:0005515	protein binding	IPI	J:182375
Molecular Function	GO:0005515	protein binding	IPI	J:123598
Molecular Function	GO:0005515	protein binding	IPI	J:175308
Molecular Function	GO:0005515	protein binding	IPI	J:131452
Molecular Function	GO:0005515	protein binding	IPI	J:162660
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IBA	J:265628
Cellular Component	GO:0000791	euchromatin	IDA	J:185349
Cellular Component	GO:0035097	histone methyltransferase complex	TAS	J:185349
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:73065
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:123598
Cellular Component	GO:0071339	MLL1 complex	IDA	J:156231
Cellular Component	GO:0071339	MLL1 complex	ISO	J:164563
Cellular Component	GO:0044665	MLL1/2 complex	ISO	J:164563
Cellular Component	GO:0044666	MLL3/4 complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617960
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619424
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619430
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619434
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619436
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619437
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619440
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621004
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621012
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810150
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810169
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810170
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:123598
Cellular Component	GO:0048188	Set1C/COMPASS complex	ISO	J:164563
Cellular Component	GO:0048188	Set1C/COMPASS complex	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	ISO	J:123598
Biological Process	GO:0051568	histone H3-K4 methylation	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:162660
Biological Process	GO:0043627	response to estrogen	ISO	J:164563
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	NAS	J:185349
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ISO	J:164563