GO Annotations Graph

• Symbol: Cib1
• Name: calcium and integrin binding 1
• ID: MGI:1344418

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISS	J:114117
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0008427	calcium-dependent protein kinase inhibitor activity	ISO	J:164563
Molecular Function	GO:0000287	magnesium ion binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:163320
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0030291	protein serine/threonine kinase inhibitor activity	ISO	J:164563
Molecular Function	GO:0043495	protein-membrane adaptor activity	ISO	J:164563
Molecular Function	GO:0043495	protein-membrane adaptor activity	IMP	J:163320
Molecular Function	GO:0043495	protein-membrane adaptor activity	IBA	J:265628
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:163320
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0071944	cell periphery	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IMP	J:113844
Cellular Component	GO:0005737	cytoplasm	IDA	J:163320
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISS	J:113844
Cellular Component	GO:0032433	filopodium tip	ISO	J:164563
Cellular Component	GO:0030426	growth cone	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:113844
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISS	J:113844
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	IDA	J:163320
Cellular Component	GO:0042383	sarcolemma	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0006915	apoptotic process	ISS	J:113844
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0071363	cellular response to growth factor stimulus	IDA	J:141569
Biological Process	GO:0071363	cellular response to growth factor stimulus	IDA	J:181770
Biological Process	GO:0071363	cellular response to growth factor stimulus	IBA	J:265628
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	ISO	J:164563
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0031122	cytoplasmic microtubule organization	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISS	J:113989
Biological Process	GO:0007113	endomitotic cell cycle	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:114645
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045653	negative regulation of megakaryocyte differentiation	IMP	J:181770
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	ISO	J:164563
Biological Process	GO:0010977	negative regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IMP	J:181770
Biological Process	GO:0001933	negative regulation of protein phosphorylation	IMP	J:181770
Biological Process	GO:0030220	platelet formation	IMP	J:181770
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	ISO	J:164563
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	IMP	J:163320
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	ISO	J:155856
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	IBA	J:265628
Biological Process	GO:0043085	positive regulation of catalytic activity	IMP	J:141569
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	IMP	J:114645
Biological Process	GO:0030335	positive regulation of cell migration	IMP	J:181770
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	IMP	J:141569
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:141569
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	IMP	J:181770
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:141569
Biological Process	GO:2000256	positive regulation of male germ cell proliferation	IMP	J:114645
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	IMP	J:163320
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	IBA	J:265628
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IMP	J:141569
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	IMP	J:141569
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:164563
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ISO	J:164563
Biological Process	GO:0051302	regulation of cell division	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0002931	response to ischemia	IDA	J:141569
Biological Process	GO:0007286	spermatid development	IMP	J:114645
Biological Process	GO:0007283	spermatogenesis	IEA	J:60000
Biological Process	GO:0038163	thrombopoietin-mediated signaling pathway	IMP	J:181770