GO Annotations Graph

• Symbol: Pglyrp1
• Name: peptidoglycan recognition protein 1
• ID: MGI:1345092

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IEA	J:60000
Molecular Function	GO:0030544	Hsp70 protein binding	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	IEA	J:72247
Molecular Function	GO:0042834	peptidoglycan binding	ISO	J:164563
Molecular Function	GO:0042834	peptidoglycan binding	IBA	J:265628
Molecular Function	GO:0016019	peptidoglycan immune receptor activity	ISO	J:164563
Molecular Function	GO:0016019	peptidoglycan immune receptor activity	IBA	J:265628
Molecular Function	GO:0016019	peptidoglycan immune receptor activity	ISO	J:71500
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0051701	biological process involved in interaction with host	IMP	J:178053
Biological Process	GO:0042742	defense response to bacterium	IEA	J:60000
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IBA	J:265628
Biological Process	GO:0016045	detection of bacterium	ISO	J:164563
Biological Process	GO:0016045	detection of bacterium	IBA	J:265628
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:72247
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0031640	killing of cells of another organism	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:178054
Biological Process	GO:0032827	negative regulation of natural killer cell differentiation involved in immune response	IMP	J:178053
Biological Process	GO:0032689	negative regulation of type II interferon production	IMP	J:178053
Biological Process	GO:0009253	peptidoglycan catabolic process	IEA	J:72247
Biological Process	GO:0009617	response to bacterium	IEP	J:190322