GO Annotations Graph

• Symbol: Pacsin2
• Name: protein kinase C and casein kinase substrate in neurons 2
• ID: MGI:1345153

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	IDA	J:66805
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IDA	J:158755
Molecular Function	GO:0070300	phosphatidic acid binding	ISO	J:164563
Molecular Function	GO:0005543	phospholipid binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Cellular Component	GO:0005901	caveola	ISO	J:164563
Cellular Component	GO:0005901	caveola	IDA	J:183061
Cellular Component	GO:0005901	caveola	ISO	J:201740
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:66805
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:56265
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0019898	extrinsic component of membrane	IDA	J:158755
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:200757
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:200757
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:200757
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0055038	recycling endosome membrane	ISO	J:164563
Biological Process	GO:0030036	actin cytoskeleton organization	IEA	J:72247
Biological Process	GO:0070836	caveola assembly	ISO	J:164563
Biological Process	GO:0072584	caveolin-mediated endocytosis	ISO	J:164563
Biological Process	GO:0048858	cell projection morphogenesis	IMP	J:158755
Biological Process	GO:0007010	cytoskeleton organization	IBA	J:265628
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:200757
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:200757
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:200757
Biological Process	GO:0045806	negative regulation of endocytosis	IDA	J:66805
Biological Process	GO:0097320	plasma membrane tubulation	IMP	J:158755
Biological Process	GO:0097320	plasma membrane tubulation	ISO	J:164563
Biological Process	GO:0097320	plasma membrane tubulation	IBA	J:265628
Biological Process	GO:0036010	protein localization to endosome	ISO	J:164563
Biological Process	GO:0030100	regulation of endocytosis	IBA	J:265628
Biological Process	GO:0007165	signal transduction	TAS	J:56265