GO Annotations Graph

• Symbol: Nlrp5
• Name: NLR family, pyrin domain containing 5
• ID: MGI:1345193

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:284116
Molecular Function	GO:0005515	protein binding	IPI	J:276268
Molecular Function	GO:0005515	protein binding	IPI	J:296111
Molecular Function	GO:0005515	protein binding	IPI	J:140105
Molecular Function	GO:0005515	protein binding	IPI	J:140105
Molecular Function	GO:0005515	protein binding	IPI	J:302234
Molecular Function	GO:0005515	protein binding	IPI	J:130427
Molecular Function	GO:0005515	protein binding	IPI	J:130427
Molecular Function	GO:0005515	protein binding	IPI	J:140105
Molecular Function	GO:0015631	tubulin binding	ISO	J:164563
Cellular Component	GO:0045179	apical cortex	IDA	J:130427
Cellular Component	GO:0045179	apical cortex	IDA	J:130427
Cellular Component	GO:0045179	apical cortex	IDA	J:130427
Cellular Component	GO:0005938	cell cortex	IDA	J:276268
Cellular Component	GO:0005938	cell cortex	IDA	J:284116
Cellular Component	GO:0005938	cell cortex	IBA	J:265628
Cellular Component	GO:0005938	cell cortex	IDA	J:140105
Cellular Component	GO:0005938	cell cortex	IDA	J:130427
Cellular Component	GO:0005938	cell cortex	IDA	J:148330
Cellular Component	GO:0060473	cortical granule	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:284116
Cellular Component	GO:0005737	cytoplasm	IDA	J:296111
Cellular Component	GO:0005737	cytoplasm	IDA	J:165134
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:56809
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:88687
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	IDA	J:88687
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:1990917	ooplasm	IDA	J:130427
Cellular Component	GO:0032991	protein-containing complex	IDA	J:140105
Cellular Component	GO:0032991	protein-containing complex	IDA	J:130427
Cellular Component	GO:0106333	subcortical maternal complex	ISO	J:164563
Cellular Component	GO:0106333	subcortical maternal complex	IDA	J:284116
Cellular Component	GO:0106333	subcortical maternal complex	IDA	J:296111
Cellular Component	GO:0106333	subcortical maternal complex	IDA	J:140105
Cellular Component	GO:0106333	subcortical maternal complex	IDA	J:130427
Cellular Component	GO:0106333	subcortical maternal complex	IBA	J:265628
Cellular Component	GO:0106333	subcortical maternal complex	IDA	J:302234
Biological Process	GO:0007015	actin filament organization	IMP	J:276268
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:61078
Biological Process	GO:0060471	cortical granule exocytosis	IMP	J:278740
Biological Process	GO:0007566	embryo implantation	IMP	J:140105
Biological Process	GO:0051656	establishment of organelle localization	IMP	J:278740
Biological Process	GO:0051656	establishment of organelle localization	IMP	J:206880
Biological Process	GO:0051293	establishment of spindle localization	IMP	J:276268
Biological Process	GO:0006887	exocytosis	IMP	J:206880
Biological Process	GO:0009566	fertilization	IMP	J:65518
Biological Process	GO:0009566	fertilization	IMP	J:140105
Biological Process	GO:0001701	in utero embryonic development	IMP	J:65518
Biological Process	GO:0001701	in utero embryonic development	IMP	J:140105
Biological Process	GO:0040019	positive regulation of embryonic development	IMP	J:185833
Biological Process	GO:0008104	protein localization	IMP	J:165134
Biological Process	GO:0065003	protein-containing complex assembly	IMP	J:140105
Biological Process	GO:0051302	regulation of cell division	IMP	J:276268
Biological Process	GO:0050727	regulation of inflammatory response	IBA	J:265628
Biological Process	GO:0032879	regulation of localization	IMP	J:185833
Biological Process	GO:0031647	regulation of protein stability	IMP	J:130427
Biological Process	GO:0043487	regulation of RNA stability	IMP	J:65518