Slc11a2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
MGI:1345279

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046870	cadmium ion binding	ISO	J:164563
Molecular Function	GO:0046870	cadmium ion binding	ISO	J:155856
Molecular Function	GO:0046870	cadmium ion binding	IBA	J:265628
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0050897	cobalt ion binding	ISO	J:155856
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	IDA	J:83962
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	IDA	J:84408
Molecular Function	GO:0005507	copper ion binding	ISO	J:155856
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0022890	inorganic cation transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005506	iron ion binding	ISO	J:155856
Molecular Function	GO:0005381	iron ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015094	lead ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015094	lead ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015094	lead ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015094	lead ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0030145	manganese ion binding	ISO	J:155856
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0046873	metal ion transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0016151	nickel cation binding	ISO	J:155856
Molecular Function	GO:0015099	nickel cation transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015099	nickel cation transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015099	nickel cation transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:1905394	retromer complex binding	ISO	J:164563
Molecular Function	GO:0015295	solute:proton symporter activity	ISO	J:164563
Molecular Function	GO:0046915	transition metal ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015100	vanadium ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:155856
Cellular Component	GO:0045177	apical part of cell	ISO	J:155856
Cellular Component	GO:0045177	apical part of cell	ISO	J:164563
Cellular Component	GO:0045177	apical part of cell	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0045178	basal part of cell	ISO	J:164563
Cellular Component	GO:0031526	brush border membrane	IGI	J:151027
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005769	early endosome	IBA	J:265628
Cellular Component	GO:0005768	endosome	IDA	J:103440
Cellular Component	GO:1903561	extracellular vesicle	IDA	J:236091
Cellular Component	GO:1903561	extracellular vesicle	ISO	J:164563
Cellular Component	GO:1903561	extracellular vesicle	IBA	J:265628
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	ISO	J:155856
Cellular Component	GO:0031902	late endosome membrane	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	IBA	J:265628
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	IBA	J:265628
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0070826	paraferritin complex	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:236091
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:103440
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0055037	recycling endosome	IBA	J:265628
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Cellular Component	GO:0005773	vacuole	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0070574	cadmium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0070574	cadmium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0006824	cobalt ion transport	ISO	J:164563
Biological Process	GO:0006824	cobalt ion transport	IDA	J:84408
Biological Process	GO:0098705	copper ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0006825	copper ion transport	ISO	J:164563
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:146816
Biological Process	GO:0048821	erythrocyte development	IMP	J:98088
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:5555
Biological Process	GO:0006783	heme biosynthetic process	IMP	J:115416
Biological Process	GO:0033212	iron import into cell	ISO	J:164563
Biological Process	GO:0033212	iron import into cell	IBA	J:265628
Biological Process	GO:0033212	iron import into cell	IMP	J:115416
Biological Process	GO:0034755	iron ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006826	iron ion transport	ISO	J:164563
Biological Process	GO:0006826	iron ion transport	ISO	J:155856
Biological Process	GO:0006826	iron ion transport	ISO	J:164563
Biological Process	GO:0006826	iron ion transport	IMP	J:100202
Biological Process	GO:0006826	iron ion transport	IMP	J:5555
Biological Process	GO:0015692	lead ion transport	ISO	J:164563
Biological Process	GO:0015692	lead ion transport	ISO	J:164563
Biological Process	GO:0007611	learning or memory	IMP	J:146816
Biological Process	GO:0006828	manganese ion transport	ISO	J:164563
Biological Process	GO:0006828	manganese ion transport	ISO	J:164563
Biological Process	GO:0030001	metal ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	ISO	J:164563
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IBA	J:265628
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IMP	J:135448
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IMP	J:5293
Biological Process	GO:0015675	nickel cation transport	ISO	J:164563
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	IMP	J:5985
Biological Process	GO:0006778	porphyrin-containing compound metabolic process	IMP	J:31039
Biological Process	GO:0001666	response to hypoxia	IBA	J:265628
Biological Process	GO:0010042	response to manganese ion	ISO	J:155856
Biological Process	GO:0000041	transition metal ion transport	ISO	J:155856
Biological Process	GO:0015676	vanadium ion transport	ISO	J:164563

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