GO Annotations Graph

• Symbol: Trib3
• Name: tribbles pseudokinase 3
• ID: MGI:1345675

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0019899	enzyme binding	IPI	J:110012
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:110012
Molecular Function	GO:0005515	protein binding	IPI	J:113933
Molecular Function	GO:0005515	protein binding	IPI	J:83554
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IPI	J:113933
Molecular Function	GO:0004860	protein kinase inhibitor activity	IEA	J:60000
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:83554
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:110012
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IDA	J:161158
Molecular Function	GO:0055106	ubiquitin-protein transferase regulator activity	IDA	J:161158
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9644327
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:83554
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0032869	cellular response to insulin stimulus	IDA	J:113933
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:83554
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:83554
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IMP	J:124706
Biological Process	GO:0045717	negative regulation of fatty acid biosynthetic process	IMP	J:110012
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0006469	negative regulation of protein kinase activity	IDA	J:113933
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	TAS	J:161158
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0032092	positive regulation of protein binding	IDA	J:110012
Biological Process	GO:0045732	positive regulation of protein catabolic process	IC	J:110012
Biological Process	GO:0051443	positive regulation of ubiquitin-protein transferase activity	IDA	J:110012
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0010506	regulation of autophagy	ISO	J:155856
Biological Process	GO:0010827	regulation of glucose transmembrane transport	IDA	J:113933
Biological Process	GO:0043405	regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043405	regulation of MAP kinase activity	IBA	J:265628
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563