GO Annotations Graph

• Symbol: Coro1a
• Name: coronin, actin binding protein 1A
• ID: MGI:1345961

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051015	actin filament binding	IDA	J:141431
Molecular Function	GO:0003785	actin monomer binding	ISO	J:164563
Molecular Function	GO:0008092	cytoskeletal protein binding	IMP	J:100752
Molecular Function	GO:0042802	identical protein binding	IPI	J:100752
Molecular Function	GO:0032036	myosin heavy chain binding	ISO	J:164563
Molecular Function	GO:0043548	phosphatidylinositol 3-kinase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:230442
Molecular Function	GO:0005515	protein binding	IPI	J:207835
Molecular Function	GO:0005515	protein binding	IPI	J:141431
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:100752
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0030424	axon	IDA	J:207835
Cellular Component	GO:0031252	cell leading edge	IDA	J:141431
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005769	early endosome	IDA	J:207835
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:208639
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:208639
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:208639
Cellular Component	GO:0001772	immunological synapse	ISO	J:164563
Cellular Component	GO:0001772	immunological synapse	IDA	J:131363
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0001891	phagocytic cup	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:100752
Cellular Component	GO:0005886	plasma membrane	IDA	J:131363
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032426	stereocilium tip	EXP	J:230827
Cellular Component	GO:0045202	synapse	IDA	J:208639
Cellular Component	GO:0045202	synapse	IDA	J:208639
Cellular Component	GO:0045202	synapse	IDA	J:208639
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0007015	actin filament organization	IMP	J:131363
Biological Process	GO:0006816	calcium ion transport	IMP	J:141431
Biological Process	GO:0006816	calcium ion transport	IMP	J:131363
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0031589	cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0071353	cellular response to interleukin-4	IDA	J:62630
Biological Process	GO:0061502	early endosome to recycling endosome transport	IMP	J:207835
Biological Process	GO:0010631	epithelial cell migration	IMP	J:111593
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:131363
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:141431
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IMP	J:141431
Biological Process	GO:0030595	leukocyte chemotaxis	IMP	J:111593
Biological Process	GO:0043320	natural killer cell degranulation	ISO	J:164563
Biological Process	GO:0051126	negative regulation of actin nucleation	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:207835
Biological Process	GO:0031339	negative regulation of vesicle fusion	IMP	J:207835
Biological Process	GO:0038180	nerve growth factor signaling pathway	IGI	J:207835
Biological Process	GO:0038180	nerve growth factor signaling pathway	IGI	J:207835
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:207835
Biological Process	GO:0006909	phagocytosis	ISO	J:164563
Biological Process	GO:0001845	phagolysosome assembly	ISO	J:164563
Biological Process	GO:0050918	positive chemotaxis	ISO	J:164563
Biological Process	GO:0050870	positive regulation of T cell activation	IMP	J:131363
Biological Process	GO:2000406	positive regulation of T cell migration	IMP	J:131363
Biological Process	GO:0042102	positive regulation of T cell proliferation	IMP	J:131363
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0030833	regulation of actin filament polymerization	IMP	J:141431
Biological Process	GO:0008064	regulation of actin polymerization or depolymerization	IMP	J:111593
Biological Process	GO:0008360	regulation of cell shape	IMP	J:141431
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	IGI	J:207835
Biological Process	GO:0034097	response to cytokine	IMP	J:141431
Biological Process	GO:0042110	T cell activation	IMP	J:131363
Biological Process	GO:0043029	T cell homeostasis	IMP	J:111593
Biological Process	GO:0043029	T cell homeostasis	IMP	J:111593
Biological Process	GO:0043029	T cell homeostasis	IMP	J:111593
Biological Process	GO:0072678	T cell migration	IMP	J:131363
Biological Process	GO:0042098	T cell proliferation	IMP	J:131363
Biological Process	GO:0072679	thymocyte migration	IMP	J:141431
Biological Process	GO:0032796	uropod organization	IMP	J:111593
Biological Process	GO:0006906	vesicle fusion	IMP	J:207835