GO Annotations Graph

• Symbol: Coro1b
• Name: coronin, actin binding protein 1B
• ID: MGI:1345963

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0071933	Arp2/3 complex binding	ISO	J:155856
Molecular Function	GO:0071933	Arp2/3 complex binding	ISO	J:164563
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:141431
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0031252	cell leading edge	ISO	J:164563
Cellular Component	GO:0031252	cell leading edge	ISO	J:155856
Cellular Component	GO:0071944	cell periphery	ISO	J:155856
Cellular Component	GO:0071944	cell periphery	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	ISO	J:155856
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0090135	actin filament branching	ISO	J:164563
Biological Process	GO:0051017	actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	ISO	J:164563
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	ISO	J:155856
Biological Process	GO:0035767	endothelial cell chemotaxis	ISO	J:164563
Biological Process	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	ISO	J:164563
Biological Process	GO:2000393	negative regulation of lamellipodium morphogenesis	ISO	J:155856
Biological Process	GO:0071672	negative regulation of smooth muscle cell chemotaxis	ISO	J:155856
Biological Process	GO:0071672	negative regulation of smooth muscle cell chemotaxis	ISO	J:164563
Biological Process	GO:2000394	positive regulation of lamellipodium morphogenesis	ISO	J:164563
Biological Process	GO:0070528	protein kinase C signaling	ISO	J:155856
Biological Process	GO:1902463	protein localization to cell leading edge	ISO	J:164563
Biological Process	GO:0031529	ruffle organization	ISO	J:164563
Biological Process	GO:0042060	wound healing	ISO	J:164563