GO Annotations Graph

• Symbol: Fxr2
• Name: FMR1 autosomal homolog 2
• ID: MGI:1346074

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0003730	mRNA 3'-UTR binding	IBA	J:265628
Molecular Function	GO:0003729	mRNA binding	IEA	J:72247
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:231210
Molecular Function	GO:0005515	protein binding	IPI	J:88664
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	IBA	J:265628
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0045182	translation regulator activity	IBA	J:265628
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:75389
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	IBA	J:265628
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	IDA	J:179583
Cellular Component	GO:1902737	dendritic filopodium	IBA	J:265628
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0044326	dendritic spine neck	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263455
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263455
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263455
Cellular Component	GO:0030426	growth cone	IBA	J:265628
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005844	polysome	IBA	J:265628
Cellular Component	GO:0005844	polysome	IDA	J:179583
Cellular Component	GO:0098794	postsynapse	IDA	J:263455
Cellular Component	GO:0098794	postsynapse	IDA	J:263455
Cellular Component	GO:0098794	postsynapse	IDA	J:263455
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0098793	presynapse	IBA	J:265628
Biological Process	GO:0021542	dentate gyrus development	IMP	J:174968
Biological Process	GO:0061157	mRNA destabilization	IMP	J:174968
Biological Process	GO:0017148	negative regulation of translation	IBA	J:265628
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IBA	J:265628
Biological Process	GO:0045727	positive regulation of translation	IBA	J:265628
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IBA	J:265628
Biological Process	GO:0051489	regulation of filopodium assembly	IBA	J:265628
Biological Process	GO:0043488	regulation of mRNA stability	IBA	J:265628
Biological Process	GO:0006417	regulation of translation	IEA	J:72247