GO Annotations Graph

• Symbol: Fbln5
• Name: fibulin 5
• ID: MGI:1346091

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0030023	extracellular matrix constituent conferring elasticity	RCA	J:265607
Molecular Function	GO:0030023	extracellular matrix constituent conferring elasticity	RCA	J:265604
Molecular Function	GO:0005178	integrin binding	IDA	J:86753
Molecular Function	GO:0005515	protein binding	IPI	J:221200
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IDA	J:103848
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0071953	elastic fiber	IDA	J:86754
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2426460
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:86754
Biological Process	GO:0048251	elastic fiber assembly	IMP	J:86753
Biological Process	GO:0048251	elastic fiber assembly	ISO	J:164563
Biological Process	GO:0048251	elastic fiber assembly	IBA	J:265628
Biological Process	GO:0030198	extracellular matrix organization	IDA	J:139122
Biological Process	GO:0098867	intramembranous bone growth	IMP	J:232938
Biological Process	GO:0016525	negative regulation of angiogenesis	IMP	J:143146
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:143146
Biological Process	GO:0033690	positive regulation of osteoblast proliferation	IMP	J:232938
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:143146
Biological Process	GO:0034394	protein localization to cell surface	IMP	J:103848
Biological Process	GO:2000121	regulation of removal of superoxide radicals	IMP	J:103848
Biological Process	GO:0046903	secretion	ISO	J:164563