GO Annotations Graph

• Symbol: Nr5a1
• Name: nuclear receptor subfamily 5, group A, member 1
• ID: MGI:1346833

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:222150
Molecular Function	GO:0003682	chromatin binding	IDA	J:104056
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:84708
Molecular Function	GO:0005515	protein binding	IPI	J:84530
Molecular Function	GO:0005515	protein binding	IPI	J:82562
Molecular Function	GO:0005515	protein binding	IPI	J:84530
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:222150
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:89122
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:96928
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:84708
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9690401
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9690410
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692157
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692234
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:116374
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:222150
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IBA	J:265628
Biological Process	GO:0030325	adrenal gland development	IMP	J:101728
Biological Process	GO:0030325	adrenal gland development	IMP	J:175843
Biological Process	GO:0030325	adrenal gland development	IGI	J:74975
Biological Process	GO:0030325	adrenal gland development	IMP	J:74975
Biological Process	GO:0097720	calcineurin-mediated signaling	ISO	J:155856
Biological Process	GO:0008585	female gonad development	ISO	J:164563
Biological Process	GO:0042445	hormone metabolic process	IMP	J:175843
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISO	J:155856
Biological Process	GO:0009755	hormone-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0033327	Leydig cell differentiation	IGI	J:98517
Biological Process	GO:0001553	luteinization	IMP	J:91352
Biological Process	GO:0051457	maintenance of protein location in nucleus	IDA	J:83625
Biological Process	GO:0008584	male gonad development	ISO	J:164563
Biological Process	GO:0008584	male gonad development	IMP	J:175843
Biological Process	GO:0008584	male gonad development	IGI	J:150743
Biological Process	GO:0008584	male gonad development	IMP	J:91352
Biological Process	GO:0030238	male sex determination	ISO	J:164563
Biological Process	GO:2000195	negative regulation of female gonad development	IMP	J:147038
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:147038
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:84708
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:2000020	positive regulation of male gonad development	ISO	J:164563
Biological Process	GO:2000020	positive regulation of male gonad development	ISO	J:155856
Biological Process	GO:2000020	positive regulation of male gonad development	IMP	J:147038
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:222150
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:84530
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:178424
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:96928
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:56540
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:178424
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:82562
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:84580
Biological Process	GO:0022414	reproductive process	IMP	J:175843
Biological Process	GO:0060008	Sertoli cell differentiation	IGI	J:98517
Biological Process	GO:0007530	sex determination	ISO	J:164563
Biological Process	GO:0009888	tissue development	IBA	J:265628
Biological Process	GO:0009888	tissue development	IMP	J:101728
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:155856