GO Annotations Graph

• Symbol: Mapk9
• Name: mitogen-activated protein kinase 9
• ID: MGI:1346862

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	ISO	J:155856
Molecular Function	GO:0004705	JUN kinase activity	ISO	J:164563
Molecular Function	GO:0004705	JUN kinase activity	ISO	J:155856
Molecular Function	GO:0004705	JUN kinase activity	ISS	J:61895
Molecular Function	GO:0004705	JUN kinase activity	IBA	J:265628
Molecular Function	GO:0004705	JUN kinase activity	IDA	J:242717
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0004707	MAP kinase activity	IEA	J:72245
Molecular Function	GO:0004707	MAP kinase activity	IEA	J:72247
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:64817
Molecular Function	GO:0005515	protein binding	IPI	J:57455
Molecular Function	GO:0004672	protein kinase activity	IDA	J:230002
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0004712	protein serine/threonine/tyrosine kinase activity	IMP	J:259122
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IMP	J:259122
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:242717
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISS	J:137567
Cellular Component	GO:0005829	cytosol	IDA	J:131696
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IDA	J:131696
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IC	J:61895
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IC	J:105153
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:105153
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:105153
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:106899
Biological Process	GO:0071276	cellular response to cadmium ion	ISO	J:164563
Biological Process	GO:0034614	cellular response to reactive oxygen species	ISO	J:164563
Biological Process	GO:0034644	cellular response to UV	ISO	J:155856
Biological Process	GO:0090594	inflammatory response to wounding	IDA	J:242717
Biological Process	GO:0007254	JNK cascade	ISS	J:61895
Biological Process	GO:0007254	JNK cascade	ISO	J:155856
Biological Process	GO:0007254	JNK cascade	ISO	J:164563
Biological Process	GO:0007254	JNK cascade	IBA	J:265628
Biological Process	GO:0007258	JUN phosphorylation	ISO	J:155856
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:105153
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:105153
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IMP	J:259122
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	IGI	J:106899
Biological Process	GO:0010770	positive regulation of cell morphogenesis involved in differentiation	ISO	J:155856
Biological Process	GO:0032722	positive regulation of chemokine production	ISO	J:155856
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:155856
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IDA	J:242717
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	ISO	J:164563
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	ISO	J:155856
Biological Process	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	ISO	J:155856
Biological Process	GO:0071803	positive regulation of podosome assembly	IMP	J:211909
Biological Process	GO:0031394	positive regulation of prostaglandin biosynthetic process	ISO	J:155856
Biological Process	GO:0032308	positive regulation of prostaglandin secretion	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IMP	J:259122
Biological Process	GO:1901485	positive regulation of transcription factor catabolic process	IMP	J:259122
Biological Process	GO:0061833	protein localization to tricellular tight junction	IMP	J:230002
Biological Process	GO:0006468	protein phosphorylation	IMP	J:186089
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:230002
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:186089
Biological Process	GO:0046328	regulation of JNK cascade	ISO	J:155856
Biological Process	GO:0031396	regulation of protein ubiquitination	ISO	J:155856
Biological Process	GO:0001836	release of cytochrome c from mitochondria	ISO	J:155856
Biological Process	GO:0046686	response to cadmium ion	IGI	J:106899
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0048511	rhythmic process	IEA	J:60000